RNA m6A methylation regulates the ultraviolet-induced DNA damage response.
Temporal Control of Mammalian Cortical Neurogenesis by m6A Methylation
N 6-Methyladenosines Modulate A-to-I RNA Editing
m6A modification negatively regulates translation by switching mRNA from polysome to P-body via IGF2BP3
Inhibition of ALKBH5 attenuates I/R-induced renal injury in male mice by promoting Ccl28 m6A modification and increasing Treg recruitment - PMC
Journal
Nature communications
METTL14-mediated m6A epitranscriptomic modification contributes to chemotherapy-induced neuropathic pain by stabilizing GluN2A expression via IGF2BP2
Journal
The Journal of clinical investigation
METTL14-mediated m6A epitranscriptomic modification contributes to chemotherapy-induced neuropathic pain by stabilizing GluN2A expression via IGF2BP2
Journal
The Journal of clinical investigation
Impaired autophagic degradation of lncRNA ARHGAP5-AS1 promotes chemoresistance in gastric cancer.
Journal
Cell death & disease
DDX5 inhibits inflammation by modulating m6A levels of TLR2/4 transcripts during bacterial infection
METTL14 modulates glycolysis to inhibit colorectal tumorigenesis in p53wildtype cells
Species
Homo sapiens, Mus musculus
Targeting METTL3 reprograms the tumor microenvironment to improve cancer immunotherapy
Journal
Cell chemical biology
Species
Homo sapiens,Mus musculus
Transcriptome-wide m6A methylome during osteogenic differentiation of human adipose-derived stem cells
Journal
Stem Cell Res Ther
N6-Adenosine Methylation in RNA and a Reduced m3G/TMG Level in Non-Coding RNAs Appear at Microirradiation-Induced DNA Lesions
MEIS1 regulated proliferation and migration of pulmonary artery smooth muscle cells in hypoxia-induced pulmonary hypertension
Oxidative Stress Mediated by N6Methyladenosine Methylation Contributes to HighFat Diet Induced Male Reproductive Dysfunction
Journal
Molecular nutrition & food research
UVB promotes melanogenesis by regulating METTL3
Journal
Journal of cellular physiology
The distinct function and localization of METTL3/METTL14 and METTL16 enzymes in cardiomyocytes
Journal
International journal of molecular sciences
Pseudorabies virus exploits N6-methyladenosine modification to promote viral replication - PMC
Journal
Frontiers in microbiology
LncRNA THRIL, transcriptionally activated by AP-1 and stabilized by METTL14-mediated m6A modification, accelerates LPS-evoked acute injury in alveolar epithelial
Journal
International immunopharmacology
Downregulation of METTL14 increases apoptosis and autophagy induced by cisplatin in pancreatic cancer cells
Journal
The International Journal of Biochemistry & Cell Biology
Arsenic trioxide suppresses lung adenocarcinoma stem cell stemness by inhibiting m6A modification to promote ferroptosis - PMC
Journal
American journal of cancer research
Downregulation of m6A Methyltransferase in the Hippocampus of Tyrobp -/- Mice and Implications for Learning and Memory Deficits
Journal
Frontiers in neuroscience
m 6 A mRNA Methylation Was Associated With Gene Expression and Lipid Metabolism in Liver of Broilers Under Lipopolysaccharide Stimulation
Journal
Frontiers in genetics
Transcriptome-wide N6-methyladenosine methylation profile of atherosclerosis in mice - PMC
Comprehensive analysis of N6-methyladenosine-related RNA methylation in the mouse hippocampus after acquired hearing loss - PMC
The Comprehensive Analysis of N6-Methyadenosine Writer METTL3 and METTL14 in Gastric Cancer - PMC
Journal
Journal of oncology
The m6A mRNA demethylase FTO regulates GnRH secretion in Mn-induced precocious puberty
Journal
Mol Cell Endocrinol
Development and verification of a deep learning-based m6A modification model for clinical prognosis prediction of renal cell carcinoma
Journal
Journal of cancer research and clinical oncology
Application
WB, IHC, RIP, RT-PCR
Inhibition of METTL3/m6A/miR126 promotes the migration and invasion of endometrial stromal cells in endometriosis
METTL3/14 and IL17 signaling contribute to CEBPADT enhanced oral cancer cisplatin resistance
The expression of m6A enzymes in the hippocampus of diabetic cognitive impairment mice and the possible improvement of YTHDF1
Stage-specific requirement for m6A RNA methylation during cardiac differentiation of pluripotent stem cells
Journal
Differentiation; research in biological diversity
Downregulation of FTO in the hippocampus is associated with mental disorders induced by fear stress during pregnancy
Journal
Behavioural brain research
Expression profiling of N6-methyladenosine-modified mRNA in PC12 cells in response to unconjugated bilirubin
Journal
Molecular biology reports
METTL14 contributes to acute lung injury by stabilizing NLRP3 expression in an IGF2BP2-dependent manner - PMC
Journal
Cell death & disease
METTL14 contributes to acute lung injury by stabilizing NLRP3 expression in an IGF2BP2-dependent manner - PMC
Journal
Cell death & disease
High glucose induces tau hyperphosphorylation in hippocampal neurons via inhibition of ALKBH5-mediated Dgkh m6A demethylation: a potential mechanism for diabetic cognitive dysfunction - PMC
Journal
Cell death & disease
Species
Homo sapiens, Rattus norvegicus