Porphyromonas gingivalis infection promotes mitochondrial dysfunction through Drp1-dependent mitochondrial fission in endothelial cells
Naked mole-rat brown fat thermogenesis is diminished during hypoxia through a rapid decrease in UCP1
Cytoplasmic Escape of Mitochondrial DNA Mediated by Mfn2 Downregulation Promotes Microglial Activation via cGasSting Axis in Spinal Cord Injury
PTENα regulates mitophagy and maintains mitochondrial quality control.
Influenza M2 protein regulates MAVS-mediated signaling pathway through interacting with MAVS and increasing ROS production
Mitochondrial dynamics and mitophagy involved in MPA-capped CdTe quantum dots-induced toxicity in the human liver carcinoma (HepG2) cell line
Journal
Environmental pollution (Barking, Essex : 1987)
Altered synaptic currents, mitophagy, mitochondrial dynamics in Alzheimer's disease models and therapeutic potential of Dengzhan Shengmai Capsules
Journal
Journal of pharmaceutical analysis
20-HETE synthesis inhibition attenuates traumatic brain injury-induced mitochondrial dysfunction and neuronal apoptosis via the SIRT1/PGC-1α pathway: A translational study
TRPA1 promotes cisplatin-induced acute kidney injury via regulating the endoplasmic reticulum stress-mitochondrial damage - PMC
Journal
Journal of translational medicine
Species
Homo sapiens,Mus musculus
Double C-2 like domain beta (DOC2B) induces calcium dependent oxidative stress to promote lipotoxicity and mitochondrial dysfunction for its tumor suppressive …
Journal
Free radical biology & medicine
Cornus officinalis Sieb. attenuates A25-35-induced mitochondrial damage and neuroinflammation in mice by modulating the ERK pathway
Journal
Phytomedicine : international journal of phytotherapy and phytopharmacology
Enhancing Spns2/S1P in macrophages alleviates hyperinflammation and prevents immunosuppression in sepsis
Activation of NRF2 Signaling Pathway Delays the Progression of Hyperuricemic Nephropathy by Reducing Oxidative Stress - PMC
Journal
Antioxidants (Basel, Switzerland)
Species
Mus musculus, Rattus norvegicus
Inhibition of mitochondrial fusion via SIRT1/PDK2/PARL axis breaks mitochondrial metabolic plasticity and sensitizes cancer cells to glucose restriction
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Boosting mitochondrial function and metabolism in aging female germ cells with dual ROCK/ROS inhibition
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Chicken thalamic injury induced by copper (II) or / and arsenite exposure involves oxidative stress and inflammation-induced apoptosis
Journal
Ecotoxicology and Environmental Safety
Electrical Pulse Stimulation Protects C2C12 Myotubes against Hydrogen Peroxide-Induced Cytotoxicity via Nrf2/Antioxidant Pathway - PMC
Journal
Antioxidants (Basel, Switzerland)
Dapagliflozin improves diabetic cognitive impairment via indirectly modulating the mitochondria homeostasis of hippocampus in diabetic mice
Journal
BioFactors (Oxford, England)
Ganoderic acid improves 5-fluorouracil-induced cognitive dysfunction in mice
Role of mitochondria-endoplasmic reticulum coupling in lycopene preventing DEHP-induced hepatotoxicity
Lycopene attenuates di(2-ethylhexyl) phthalate-induced mitophagy in spleen by regulating the sirtuin3-mediated pathway
Defective Mitochondrial Dynamics and Protein Degradation Pathways Underlie Cadmium-Induced Neurotoxicity and Cell Death in Huntingtons Disease Striatal Cells - PMC
Journal
International journal of molecular sciences
Ets1 facilitates EMT/invasion through Drp1-mediated mitochondrial fragmentation in ovarian cancer - PMC
Hydrogen sulfide attenuates mitochondrial dysfunction-induced cellular senescence and apoptosis in alveolar epithelial cells by upregulating sirtuin 1.
New Insights into Baicalein's Effect on Chlorpyrifos-Induced Liver Injury in Carp: Involving Macrophage Polarization and Pyropto sis
Journal
Journal of agricultural and food chemistry
Sorafenib reduces the production of epoxyeicosatrienoic acids and leads to cardiac injury by inhibiting CYP2J in rats
Journal
Biochemical pharmacology
Ubiquitin Ligase Parkin Regulates the Stability of SARS-CoV-2 Main Protease and Suppresses Viral Replication
Journal
ACS infectious diseases
Acrolein Aggravates Secondary Brain Injury After Intracerebral Hemorrhage Through Drp1-Mediated Mitochondrial Oxidative Damage in Mice
Shen Shuai II Recipe inhibits hypoxia-induced glycolysis by preserving mitochondrial dynamics to attenuate kidney fibrosis
Journal
Journal of ethnopharmacology
hUMSCs restore ovarian function in POI mice by regulating GSK3-mediated mitochondrial dynamic imbalances in theca cells - PMC
Journal
Scientific reports
ATPAF1 deficiency impairs ATP synthase assembly and mitochondrial respiration
A high-concentrate diet induces mitochondrial dysfunction by activating the MAPK signaling pathway in the mammary gland of dairy cows
Journal
Journal of dairy science
Glucose fluctuation accelerates cardiac injury of diabetic mice via sodium-dependent glucose cotransporter 1 (SGLT1)
Journal
Arch Biochem Biophys
Modified rougan decoction attenuates hepatocyte apoptosis through ameliorating mitochondrial dysfunction by upregulated SIRT1/PGC-1 signaling pathway - PMC
Knockdown of SGLT1 prevents the apoptosis of cardiomyocytes induced by glucose fluctuation via relieving oxidative stress and mitochondrial dysfunction
Journal
Biochemistry and cell biology = Biochimie et biologie cellulaire
Celastrol Alleviates Mitochondrial Oxidative Stress and Brain Injury after Intracerebral Hemorrhage by Promoting OPA1-Dependent Mitochondrial Fusion
Mitochondrial fusion mediated by mitofusin 1 regulates macrophage mycobactericidal activity by enhancing autophagy
Journal
Infection and immunity
Schisandrin Restores the Amyloid β-Induced Impairments on Mitochondrial Function, Energy Metabolism, Biogenesis, and Dynamics in Rat Primary Hippocampal Neurons
Two polyphenols isolated from Corallodiscus flabellata BL Burtt ameliorate amyloid β-protein induced Alzheimer's disease neuronal injury by improving mitochondrial …
Journal
Behavioural brain research
Txnip Gene Knockout Ameliorated High-Fat Diet-Induced Cardiomyopathy Via Regulating Mitochondria Dynamics and Fatty Acid Oxidation - PMC
Journal
Journal of cardiovascular pharmacology
Mitochondrial Dynamics in Rat Heart Induced by 5-Fluorouracil
Journal
Medical Science Monitor : International Medical Journal of Experimental and Clinical Research
Mitochondrial dysfunction in follicles is associated with broodiness in Zhedong white goose
Journal
Animal reproduction science
Mitochondria-localized lncRNA HITT inhibits fusion by attenuating formation of mitofusin-2 homo-or heterotypic complexes
Journal
The Journal of biological chemistry
SIRT3 protects against early brain injury following subarachnoid hemorrhage via promoting mitochondrial fusion in an AMPK dependent manner