Tripartite motif 16 ameliorates nonalcoholic steatohepatitis by promoting the degradation of phospho-TAK1
UBE2M-mediated neddylation of TRIM21 regulates obesity-induced inflammation and metabolic disorders
Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation
Gremlin1 is a therapeutically targetable FGFR1 ligand that regulates lineage plasticity and castration resistance in prostate cancer
Mitochondrial fission drives neuronal metabolic burden to promote stress susceptibility in male mice
RNA binding motif 4 inhibits the replication of ebolavirus by directly targeting 3-leader region of genomic RNA - PMC
Journal
Emerging microbes & infections
CoBATCH for high-throughput single-cell epigenomic profiling
Lysine acetylation of histone acetyltransferase adaptor protein ADA2 is a mechanism of metabolic control of chromatin modification in plants
Hyodeoxycholic acid ameliorates nonalcoholic fatty liver disease by inhibiting RAN-mediated PPAR nucleus-cytoplasm shuttling - PMC
Journal
Nature communications
Improved in situ characterization of protein complex dynamics at scale with thermal proximity co-aggregation - PMC
Journal
Nature communications
ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy - PMC
Journal
Nature communications
A DNAH17 missense variant causes flagella destabilization and asthenozoospermia
Journal
The Journal of Experimental Medicine
Suppressing Mesenchymal Stromal Cell Ferroptosis Via Targeting a MetabolismEpigenetics Axis Corrects their Poor Retention and Insufficient Healing Benefits in
Journal
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
SETDB1 Methylates MCT1 Promoting Tumor Progression by Enhancing the Lactate Shuttle
Journal
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
TAOK3 Facilitates Esophageal Squamous Cell Carcinoma Progression and Cisplatin Resistance Through Augmenting Autophagy Mediated by IRGM - PMC
Journal
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
SRSF5‐Mediated Alternative Splicing of M Gene is Essential for Influenza A Virus Replication: A Host‐Directed Target Against Influenza Virus
Journal
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
The Compromised Fanconi Anemia Pathway in Prelamin AExpressing Cells Contributes to Replication StressInduced Genomic Instability
Journal
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Escherichia coliInduced cGLIS3Mediated Stress Granules Activate the NFB Pathway to Promote Intrahepatic Cholangiocarcinoma Progression
Journal
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Abnormal neocortex arealization and Sotos-like syndromeassociated behavior in Setd2 mutant mice
Human TRA2A determines influenza A virus host adaptation by regulating viral mRNA splicing
The risk variant rs11836367 contributes to breast cancer onset and metastasis by attenuating Wnt signaling via regulating NTN4 expression - PMC
NF-B factors cooperate with Su(Hw)/E4F1 to balance Drosophila/human immune responses via modulating dynamic expression of miR-210
Journal
Nucleic acids research
Application
ChIP, Co-IP, IP
Species
Drosophila melanogaster
Gestational dexamethasone exposure impacts hippocampal excitatory synaptic transmission and learning and memory function with transgenerational effects
Journal
Acta pharmaceutica Sinica. B
Epigenetic programming mediates abnormal gut microbiota and disease susceptibility in offspring with prenatal dexamethasone exposure - PMC
Journal
Cell reports. Medicine
Influenza A virus protein PB1-F2 impairs innate immunity by inducing mitophagy
Influenza M2 protein regulates MAVS-mediated signaling pathway through interacting with MAVS and increasing ROS production
Megakaryocytes mediate hyperglycemia-induced tumor metastasis
Species
Homo sapiens, Mus musculus
SARS-CoV-2 spike engagement of ACE2 primes S2 site cleavage and fusion initiation
Journal
Proc Natl Acad Sci U S A
Species
Homo sapiens, Mus musculus
Functional genomics analysis reveals the evolutionary adaptation and demographic history of pygmy lorises
Journal
Proceedings of the National Academy of Sciences of the United States of America
Species
Xanthonycticebus pygmaeus
Long noncoding RNA NEAT1 is involved in the protective effect of Klotho on renal tubular epithelial cells in diabetic kidney disease through the ERK1/2 signaling pathway
Journal
Experimental & Molecular Medicine
A Ralstonia solanacearum effector targets TGA transcription factors to subvert salicylic acid signaling
Species
Arabidopsis thaliana
Cytoplasmic HYL1 modulates miRNA-mediated translational repression
Species
Arabidopsis thaliana
The cytokinin receptor OHK4/OsHK4 regulates inflorescence architecture in rice via an IDEAL PLANT ARCHITECTURE1/WFP-mediated positive feedback circuit
Nitrogen-dependent binding of the transcription factor PBF1 contributes to the balance of protein and carbohydrate storage in maize endosperm
Comprehensive machine learning-generated classifier identifies pro-metastatic characteristics and predicts individual treatment in pancreatic cancer: A multicenter cohort study based on super-enhancer profiling - PMC
PABPC1L induces IDO1 to promote tryptophan metabolism and immune suppression in renal cell carcinoma
Species
Homo sapiens,Mus musculus
Analysis of multiple programmed cell death-related prognostic genes and functional validations of necroptosis-associated genes in oesophageal squamous cell carcinoma - PMC
Hsa_circ_0005273 facilitates breast cancer tumorigenesis by regulating YAP1-hippo signaling pathway
Journal
J Exp Clin Cancer Res
Genome-wide CRISPR screens identify PKMYT1 as a therapeutic target in pancreatic ductal adenocarcinoma
Journal
EMBO molecular medicine
Shank3 ameliorates neuronal injury after cerebral ischemia/reperfusion via inhibiting oxidative stress and inflammation
Maternally derived low glucocorticoid mediates adrenal developmental programming alteration in offspring induced by dexamethasone
Journal
The Science of the total environment
MIER2/PGC1A elicits sunitinib resistance via lipid metabolism in renal cell carcinoma
Journal
Journal of advanced research
Improved in vivo detection of atherosclerotic plaques with a tissue factor-targeting magnetic nanoprobe.
Journal
Acta biomaterialia
Sleep Deprivation Promotes Endothelial Inflammation and Atherogenesis by Reducing Exosomal miR-182-5p
Journal
Arteriosclerosis, thrombosis, and vascular biology
Loss of m 6 A methyltransferase METTL3 promotes heart regeneration and repair after myocardial injury
Sex difference in adrenal developmental toxicity induced by dexamethasone and its intrauterine programming mechanism
Journal
Pharmacological research
Hsa_circ_0068631 promotes breast cancer progression through c-Myc by binding to EIF4A3
Journal
Mol Ther Nucleic Acids
miR-320a induces pancreatic β cells dysfunction in diabetes by inhibiting MafF
Journal
Mol Ther Nucleic Acids
Overexpression of hepatic pescadillo 1 in obesity induces lipid dysregulation by inhibiting autophagy
Journal
Translational research : the journal of laboratory and clinical medicine
MORTALIN-Ca 2+ axis drives innate rituximab resistance in diffuse large B-cell lymphoma
Epigenetic inhibition of CTCF by HN1 promotes dedifferentiation and stemness of anaplastic thyroid cancer
PTPN23 [Thr] variant reduces susceptibility and tumorigenesis in esophageal squamous cell carcinoma through dephosphorylation of EGFR
K48-linked deubiquitination of VGLL4 by USP15 enhances the efficacy of tumor immunotherapy in triple-negative breast cancer
Application
ChIP, Co-IP, IP
MIR22HG inhibits breast cancer progression by stabilizing LATS2 tumor suppressor
Dnah9 mutant mice and organoid models recapitulate the clinical features of patients with PCD and provide an excellent platform for drug screening - PMC
Journal
Cell death & disease
CMPK2 is a host restriction factor that inhibits infection of multiple coronaviruses in a cell-intrinsic manner - PMC
Gut microbial metabolite deoxycholic acid facilitates Th17 differentiation through modulating cholesterol biosynthesis and participates in high-fat diet-associated colonic inflammation - PMC
TTP protects against acute liver failure by regulating CCL2 and CCL5 through m6A RNA methylation
Protein phosphatase PPM1A inhibition attenuates osteoarthritis via regulating TGF-/Smad2 signaling in chondrocytes - PMC
FGF-2 signaling in nasopharyngeal carcinoma modulates pericyte-macrophage crosstalk and metastasis
Lactylation of histone by BRD4 regulates astrocyte polarization after experimental subarachnoid hemorrhage - PMC
Journal
Journal of neuroinflammation
CircBIRC6 facilitates the malignant progression via miR-488/GRIN2D-mediated CAV1-autophagy signal axis in gastric cancer
Journal
Pharmacological research
Interference of a mammalian circRNA regulates lipid metabolism reprogramming by targeting miR-24-3p/Igf2/PI3K-AKT-mTOR and Igf2bp2/Ucp1 axis
Journal
Cellular and molecular life sciences : CMLS
Species
Oryctolagus cuniculus
mRNA m5C inhibits adipogenesis and promotes myogenesis by respectively facilitating YBX2 and SMO mRNA export in ALYREF-m5C manner
Journal
Cellular and molecular life sciences : CMLS
M1AP interacts with the mammalian ZZS complex and promotes male meiotic recombination
Targeting METTL3 reprograms the tumor microenvironment to improve cancer immunotherapy
Journal
Cell chemical biology
Species
Homo sapiens,Mus musculus
MiR-21 protected against diabetic cardiomyopathy induced diastolic dysfunction by targeting gelsolin
Journal
Cardiovascular Diabetology
FOXP2 confers oncogenic effects in prostate cancer - PMC
Downregulation of TUSC3 promotes EMT and hepatocellular carcinoma progression through LIPC/AKT axis - PMC
Journal
Journal of translational medicine
C17orf80 binds the mitochondrial genome to promote its replication
Journal
The Journal of cell biology
Design, Synthesis, and Biological Evaluations of DOT1L Peptide Mimetics Targeting the Protein-Protein Interactions between DOT1L and MLL-AF9/MLL-ENL
Journal
Journal of medicinal chemistry
HIF1 lactylation enhances KIAA1199 transcription to promote angiogenesis and vasculogenic mimicry in prostate cancer
Journal
International journal of biological macromolecules
Facile Synthesis of Antibody-Coupled Polydopamine-Coated Magnetic Graphene Oxide Composites for Efficient Immunopurification and Metabolomics Analysis of Mitochondria
Journal
Analytical chemistry
ULK phosphorylation of STX17 controls autophagosome maturation via FLNA
Journal
Journal of Cell Biology
Iron Regulatory Protein 1 Inhibits Ferritin Translation Responding to OsHV-1 Infection in Ark Clams, Scapharca Broughtonii
Species
Scapharca Broughtonii
MiR-23b Promotes Porcine Preadipocyte Differentiation via SESN3 and ACSL4 - PMC
LOX overexpression programming mediates the osteoclast mechanism of low peak bone mass in female offspring rats caused by pregnant dexamethasone exposure - PMC
Journal
Cell communication and signaling : CCS
NDRG1 facilitates lytic replication of Kaposi's sarcoma-associated herpesvirus by maintaining the stability of the KSHV helicase
N6-methyladenosine reader protein YTHDC1 regulates influenza A virus NS segment splicing and replication - PMC
Endoplasmic reticulum stress-triggered ferroptosis via the XBP1-Hrd1-Nrf2 pathway induces EMT progression in diabetic nephropathy.
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Quercetin inhibits DNA damage responses to induce apoptosis via SIRT5/PI3K/AKT pathway in non-small cell lung cancer
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
CAV3 alleviates diabetic cardiomyopathy via inhibiting NDUFA10-mediated mitochondrial dysfunction - PMC
Journal
Journal of translational medicine
Vitamin A deficiency suppresses CEACAM1 to impair colonic epithelial barrier function via downregulating microbial-derived short-chain fatty acids
EIF4A3-mediated circPRKCI expression promotes triple-negative breast cancer progression by regulating WBP2 and PI3K/AKT signaling pathway
Journal
Cell death discovery
Knockdown of METTL16 disrupts learning and memory by reducing the stability of MAT2A mRNA - PMC
Journal
Cell death discovery
NCAPD3 exerts tumor-promoting effects in prostatic cancer via dual impact on miR-30a-5p by STAT3-MALAT1 and MYC
Journal
Cell death discovery
Zika virus non-structural protein 4B interacts with DHCR7 to facilitate viral infection
An epigenetic circuit controls neurogenic programs during neocortex development
Journal
Development (Cambridge, England)
MS4A3-HSP27 target pathway reveals potential for haematopoietic disorder treatment in alimentary toxic aleukia
Albendazole exerts an anti-hepatocellular carcinoma effect through a WWOX-dependent pathway
Anti-inflammatory role and mechanism of microRNA-92b-3p in the progression of hypoxic pulmonary hypertension
Drosophila Relishmediated miR317 expression facilitates immune homeostasis restoration via inhibiting PGRPLC
Journal
European journal of immunology
Species
Drosophila melanogaster
Drosophila Relishmediated miR317 expression facilitates immune homeostasis restoration via inhibiting PGRPLC
Journal
European journal of immunology
Species
Drosophila melanogaster
TCF12 Activates TGFB2 Expression to Promote the Malignant Progression of Melanoma - PMC
Species
Homo sapiens, Mus musculus
LncRNA LINC01537 Promotes Gastric Cancer Metastasis and Tumorigenesis by Stabilizing RIPK4 to Activate NF-κB Signaling - PMC
Autophagy benefits the replication of influenza A virus in vitro.
Journal
Journal of virology
Bovine Herpesvirus 1 Productive Infection Led to Inactivation of Nrf2 Signaling through Diverse Approaches
Journal
Oxidative Medicine and Cellular Longevity
An alpha-herpesvirus employs host HEXIM1 to promote viral transcription
Journal
Journal of virology
Cumulative effects of weakly repressive regulatory regions in the 3 UTR maintain PD-1 expression homeostasis in mammals - PMC
Journal
Communications biology
Novel effects of sphingosylphosphorylcholine on the apoptosis of breast cancer via autophagy/AKT/p38 and JNK signaling.
Journal
Journal of cellular physiology
Ketogenic diet ameliorates lipid dysregulation in type 2 diabetic mice by downregulating hepatic pescadillo 1
Journal
Molecular medicine (Cambridge, Mass.)
Porcine Circovirus Type 2 Infection Activates NF-κB pathway and Cellular Inflammatory Responses through circPDCD4/miR-21/PDCD4 Axis in Porcine Kidney 15 Cell
CircRNA Profiling of Skeletal Muscle in Two Pig Breeds Reveals CircIGF1R Regulates Myoblast Differentiation via miR-16 - PMC
Journal
International journal of molecular sciences
Transcriptomic Analysis Reveals Fibroblast Growth Factor 11 (FGF11) Role in Brown Adipocytes in Thermogenic Regulation of Goats - PMC
Journal
International journal of molecular sciences
Interaction of MRPL9 and GGCT Promotes Cell Proliferation and Migration by Activating the MAPK/ERK Pathway in Papillary Thyroid Cancer - PMC
Journal
International journal of molecular sciences
6-Gingerol Ameliorates Hepatic Steatosis, Inflammation and Oxidative Stress in High-Fat Diet-Fed Mice through Activating LKB1/AMPK Signaling - PMC
Journal
International journal of molecular sciences
The m6A Methyltransferase METTL3-Mediated N6-Methyladenosine Modification of DEK mRNA to Promote Gastric Cancer Cell Growth and Metastasis - PMC
Journal
International journal of molecular sciences
A TMT-based shotgun proteomics uncovers overexpression of thrombospondin 1 as a contributor in pyrrolizidine alkaloid-induced hepatic sinusoidal obstruction syndrome
Journal
Archives of toxicology
Endothelial Shp2 deficiency controls alternative activation of macrophage preventing radiation-induced lung injury through notch signaling
The deubiquitinase USP5 promotes cholangiocarcinoma progression by stabilizing YBX1
Novel enhancers conferring compensatory transcriptional regulation of Nkx2-5 in heart development - PMC
MiR-466b-3p/HDAC7 meditates transgenerational inheritance of testicular testosterone synthesis inhibition induced by prenatal dexamethasone exposure
Journal
Biochemical pharmacology
Identification of lysine-lactylated substrates in gastric cancer cells - PMC
Translational and post-translational control of human naïve versus primed pluripotency
METTL3 Contributes to Osteosarcoma Progression by Increasing DANCR mRNA Stability via m6A Modification
Journal
Frontiers in cell and developmental biology
The Metabolites of Lactobacillus fermentum F-B9-1 Relieved Dextran Sulfate Sodium-Induced Experimental Ulcerative Colitis in Mice
Journal
Frontiers in microbiology
Fur functions as an activator of T6SS-mediated bacterial dominance and virulence in Aeromonas hydrophila - PMC
Journal
Frontiers in microbiology
Glaesserella parasuis autotransporters EspP1 and EspP2 are novel IgA-specific proteases - PMC
Journal
Frontiers in microbiology
Species
Glaesserella parasuis
Determination of the Interaction and Pharmacological Modulation of MCHR1 Signaling by the C-Terminus of MRAP2 Protein
Journal
Frontiers in endocrinology
miR-275/305 cluster is essential for maintaining energy metabolic homeostasis by the insulin signaling pathway in Bactrocera dorsalis - PMC
Species
Drosophila melanogaster
Increased plasma renin by vasodilators promotes the progression of abdominal aortic aneurysm - PMC
Journal
Frontiers in pharmacology
lncRNA HCG11 suppresses cell proliferation in hormone receptor-positive breast cancer via SRSF1/β-catenin - PMC
FSIP2 plays a role in the acrosome development during spermiogenesis
Journal
Journal of medical genetics
A programmable CRISPR/dCas9-based epigenetic editing system enabling loci-targeted histone citrullination and precise transcription regulation
Journal
Journal of genetics and genomics = Yi chuan xue bao
Epigenomic features associated with body temperature stabilize tissues during cold exposure in cold-resistant pigs
Journal
Journal of genetics and genomics = Yi chuan xue bao
STUB1 is acetylated by KAT5 and alleviates myocardial ischemia-reperfusion injury through LATS2-YAP--catenin axis
Journal
Communications biology
Species
Homo sapiens,Mus musculus
STUB1 is acetylated by KAT5 and alleviates myocardial ischemia-reperfusion injury through LATS2-YAP--catenin axis
Journal
Communications biology
Species
Homo sapiens,Mus musculus
SALL1 regulates commitment of odontoblast lineages by interacting with RUNX2 to remodel open chromatin regions
Interaction between PHB2 and Enterovirus A71 VP1 Induces Autophagy and Affects EV-A71 Infection
Pluripotency state transition of embryonic stem cells requires the turnover of histone chaperone FACT on chromatin
IGF2BP3 promotes progression of gallbladder carcinoma by stabilizing KLK5 mRNA in N6-methyladenosine-dependent binding - PMC
Journal
Frontiers in oncology
Ring finger protein 128 promotes, rather than inhibits, colorectal cancer progression by regulating the Hippo signaling pathway - PMC
Journal
Frontiers in oncology
Phosphorylation of ATF2 promotes odontoblastic differentiation via intrinsic HAT activity
Journal
Journal of genetics and genomics = Yi chuan xue bao
Application
CUT&Tag, ChIP, Co-IP
E2F1-mediated ectopic expression of PP1A promotes breast cancer progression via activation of YAP1
Journal
The international journal of biochemistry & cell biology
H9N2 Avian Influenza Virus Downregulates FcRY Expression in Chicken Macrophage Cell Line HD11 by Activating the JNK MAPK Pathway - PMC
Journal
International journal of molecular sciences
H9N2 Avian Influenza Virus Downregulates FcRY Expression in Chicken Macrophage Cell Line HD11 by Activating the JNK MAPK Pathway - PMC
Journal
International journal of molecular sciences
Decreased levels of H3K9ac and H3K27ac in the promotor region of ovarian P450 aromatase mediated low estradiol synthesis in female offspring rats induced by prenatal nicotine exposure as well as in human granulosa cells after nicotine treatment.
Journal
Food and chemical toxicology
Reduced testicular steroidogenesis in rat offspring by prenatal nicotine exposure: Epigenetic programming and heritability via nAChR/HDAC4
Journal
Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association
PINK1/Parkin-mediated mitophagy mitigates T-2 toxin-induced nephrotoxicity
Journal
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Maternal obesity aggravates the abnormality of porcine placenta by increasing N6-methyladenosine
Journal
International journal of obesity (2005)
Deletion of Bak1 alleviates microglial necroptosis and neuroin ammation after experimental subarachnoid hemorrhage
Journal
Journal of neurochemistry
Nuclear autoantigenic sperm protein facilitates glioblastoma progression and radioresistance by regulating the ANXA2/STAT3 axis - PMC
Journal
CNS neuroscience & therapeutics
Shrimp Plasma MANF Works as an Invertebrate Anti-Inflammatory Factor via a Conserved Receptor Tyrosine Phosphatase
Journal
Journal of immunology (Baltimore, Md. : 1950)
Interaction of lncRNA-CR33942 with Dif/Dorsal Facilitates Antimicrobial Peptide Transcriptions and Enhances Drosophila Toll Immune Responses
Journal
Journal of immunology (Baltimore, Md. : 1950)
Species
Drosophila melanogaster
Antimicrobial Protein LECT2-b Helps Maintain Gut Microbiota Homeostasis via Selectively Targeting Certain Pathogenic Bacteria
Journal
Journal of immunology (Baltimore, Md. : 1950)
Species
Ctenopharyngodon idellus
Proteomics Analysis Identifies IRSp53 and Fascin as Critical for PRV Egress and Direct Cell-Cell Transmission.
Species
Cricetulus barabensis
Quantitative Proteomics Identified TTC4 as a TBK1 Interactor and a Positive Regulator of SeV-induced Innate Immunity
Epithelial‑derived exosomes promote M2 macrophage polarization via Notch2/SOCS1 during mechanical ventilation
Journal
International journal of molecular medicine
Effects of methylation and transcription factor YY1 on ID2 expression in non-small cell lung carcinoma cells - PMC
Journal
American journal of cancer research
Early growth response protein 1 upregulates long noncoding RNA Arid2-IR to promote extracellular matrix production in diabetic kidney disease.
Journal
American journal of physiology. Cell physiology
Chaperonin TRiC/CCT subunit CCT7 is involved in the replication of canine parvovirus in F81 cells - PMC
Journal
Frontiers in microbiology
Knockdown of UBE2I inhibits tumorigenesis and enhances chemosensitivity of cholangiocarcinoma via modulating p27kip1 nuclear export
Journal
Molecular carcinogenesis
DDIT3/CHOP promotes autophagy in chondrocytes via SIRT1-AKT pathway
Journal
Biochim Biophys Acta Mol Cell Res
Fibulin-3 regulates the inhibitory effect of TNF- on chondrocyte differentiation partially via the TGF-/Smad3 signaling pathway
Journal
Biochimica et biophysica acta. Molecular cell research
Arctigenin induces activated HSCs quiescence via AMPK-PPAR pathway to ameliorate liver fibrosis in mice
Journal
European journal of pharmacology
Ubiquitin C-terminal hydrolase L1 (UCHL1) regulates post-myocardial infarction cardiac fibrosis through glucose-regulated protein of 78 kDa (GRP78)
Microfibrillar-associated protein 5 suppresses adipogenesis by inhibiting essential coactivator of PPAR - PMC
Journal
Scientific reports
Prognostic Biomarker NUMB Is Inhibited by Breast Cancer Cell Exosomes to Promote Breast Cancer Progression
Journal
Journal of immunology research
CircNCX1 modulates cardiomyocyte proliferation through promoting ubiquitination of BRG1
Journal
Cellular signalling
Xbp1 promotes odontoblastic differentiation through modulating mitochondrial homeostasis
Journal
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
LncRNA HOST2 promotes NSUN2-mediated breast cancer progression via interaction with ELAVL1
Journal
Cellular signalling
CFIm25 regulates human stem cell function independently of its role in mRNA alternative polyadenylation
Short-Chain Fatty Acid Decreases the Expression of CEBPB to Inhibit miR-145-Mediated DUSP6 and Thus Further Suppresses Intestinal Inflammation
Co-exposure of avermectin and imidacloprid induces DNA damage, pyroptosis, and immune dysfunction in epithelioma papulosum cyprini cells via ROS-mediated
Journal
Fish & shellfish immunology
Melatonin ameliorates imidacloprid-induced intestinal injury by negatively regulating the PGN/P38MAPK pathway in the common carp (Cyprinus carpio)
Journal
Fish & shellfish immunology
Caffeine programs hepatic SIRT1-related cholesterol synthesis and hypercholesterolemia via A2AR/cAMP/PKA pathway in adult male offspring rats.
Decreased H3K9ac level of StAR mediated testicular dysplasia induced by prenatal dexamethasone exposure in male offspring rats.
A pan-cancer characterization of immune-related NFIL3 identifies potential predictive biomarker - PMC
A serpin (CvT‐serpin15) of teratocytes contributes to microbial‐resistance in Plutella xylostella during Cotesia vestalis parasitism
Journal
Pest management science
Species
Plutella xylostella
Epigenetic repression of AT2 receptor is involved in cell dysfunction and glucose intolerance of adult female offspring rats exposed to dexamethasone prenatally
Journal
Toxicol Appl Pharmacol
ZDHHC17 participates in the pathogenesis of polycystic ovary syndrome by affecting androgen conversion to estrogen in granulosa cells
Journal
Molecular and cellular endocrinology
GTPase Activity of MxB Contributes to Its Nuclear Location, Interaction with Nucleoporins and Anti-HIV-1 Activity
Cadmium exposure-induced rat testicular dysfunction and its mechanism of chronic stress
Journal
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Decreased H3K9ac level of KLF4 mediates podocyte developmental toxicity induced by prenatal caffeine exposure in male offspring rats.
Journal
Toxicology letters
PGC-1 Inhibits Schwann Cell Dedifferentiation and Delays Peripheral Nerve Degeneration by Targeting PON1
Journal
Cellular and molecular neurobiology
Species
Mus musculus, Rattus norvegicus
Dynamic alterations in serum IgG N-glycan profiles in the development of colitis-associated colon Cancer in mouse model
Journal
Biochim Biophys Acta Gen Subj
TRPV3 regulates Breast Cancer Cell Proliferation and Apoptosis by EGFR/AKT pathway - PMC
Stage-, dose-, and course-dependent inhibition of prenatal amoxicillin exposure on fetal articular cartilage development in fetal mice
Journal
Toxicology and applied pharmacology
MxB impedes the NUP358-mediated HIV-1 pre-integration complex nuclear import and viral replication cooperatively with CPSF6
Shrimp MANF maintains hemocyte viability via interaction with a tyrosine kinase Abl
Journal
Developmental and comparative immunology
lncRNA-CR46018 positively regulates the Drosophila Toll immune response by interacting with Dif/Dorsal
Journal
Developmental and comparative immunology
17β‐Estradiol via Orai1 activates calcium mobilization to induce cell proliferation in epithelial ovarian cancer
Journal
Journal of biochemical and molecular toxicology
Analyzing the interactions of mRNAs, miRNAs and lncRNAs to predict ceRNA networks in bovine cystic follicular granulosa cells - PMC
Journal
Frontiers in veterinary science
SNW1 regulates Notch signaling in neuroblastoma through interacting with RBPJ.
Journal
Biochemical and biophysical research communications
β-cantenin is potentially involved in the regulation of c-Jun signaling following bovine herpesvirus 1 infection
LncRNA LINC00281/Annexin A2 Regulates Vascular Smooth Muscle Cell Phenotype Switching via the Nuclear Factor-Kappa B Signaling Pathway
Journal
Journal of cardiovascular translational research
RBM25 binds to and regulates alternative splicing levels of Slc38a9, Csf1, and Coro6 to affect immune and inflammatory processes in H9c2 cells - PMC
Species
Oryctolagus cuniculus
Fascin actin-bundling protein 1 regulates non-small cell lung cancer progression by influencing the transcription and splicing of tumorigenesis-related genes - PMC
Notch2 Regulates the Function of Bovine Follicular Granulosa Cells via the Wnt2/-Catenin Signaling Pathway - PMC
Journal
Animals : an open access journal from MDPI
4-phenylbutyric acid re-trafficking hERG/G572R channel protein by modulating the endoplasmic reticulum stress-associated chaperones and endoplasmic reticulum-associated degradation gene - PMC
Journal
Journal of thoracic disease
TRPV1 and GABAB1 in the Cerebrospinal Fluid-Contacting Nucleus are Jointly Involved in Chronic Inflammatory Pain in Rats - PMC
Journal
Journal of pain research
The expression and significance of PD-L1 in condyloma acuminatum - PMC
Journal
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
BDH1-mediated LRRC31 regulation dependent on histone lysine -hydroxybutyrylation to promote lung adenocarcinoma progression - PMC
Histone methylation mediated by NSD1 is required for the establishment and maintenance of neuronal identities
ANXA9 facilitates S100A4 and promotes breast cancer progression through modulating STAT3 pathway - PMC
Journal
Cell death & disease
Disturbed rhythmicity of intestinal hydrogen peroxide alters gut microbial oscillations in BMAL1-deficient monkeys
Mapping Active Gene-Associated Chromatin Loops by ChIA-PET in Rice
Journal
Methods in molecular biology (Clifton, N.J.)
Species
Oryza sativa,Other
CUT&Tag for Mapping In Vivo Protein-DNA Interactions in Plants
Journal
Methods in molecular biology (Clifton, N.J.)
Type I interferon/STAT1 signaling regulates UBE2M-mediated antiviral innate immunity in a negative feedback manner
Species
Homo sapiens, Mus musculus
NRP1 promotes prostate cancer progression via modulating EGFR-dependent AKT pathway activation - PMC
Journal
Cell death & disease
A novel lncRNA MDHDH suppresses glioblastoma multiforme by acting as a scaffold for MDH2 and PSMA1 to regulate NAD+ metabolism and autophagy - PMC
Journal
Journal of experimental & clinical cancer research : CR
CTGF Promotes the Osteoblast Differentiation of Human Periodontal Ligament Stem Cells by Positively Regulating BMP2/Smad Signal Transduction - PMC
Journal
BioMed research international