Asialoglycoprotein receptor 1 promotes SARS-CoV-2 infection of human normal hepatocytes - PMC
Journal
Signal transduction and targeted therapy
Smad3 methylation by EZH2 promotes its activation and tumor metastasis
Journal
The Journal of clinical investigation
Structural basis of the subcortical maternal complex and its implications in reproductive disorders
Journal
Nature structural & molecular biology
Structural basis of the substrate recognition and inhibition mechanism of Plasmodium falciparum nucleoside transporter PfENT1 - PMC
Journal
Nature communications
PHGDH arginine methylation by PRMT1 promotes serine synthesis and represents a therapeutic vulnerability in hepatocellular carcinoma - PMC
Journal
Nature communications
PD-L1 methylation restricts PD-L1/PD-1 interactions to control cancer immune surveillance - PMC
MAR1 links membrane adhesion to membrane merger during cell-cell fusion in Chlamydomonas
Journal
Developmental cell
Autophagy contributes to sulfonylurea herbicide tolerance via GCN2-independent regulation of amino acid homeostasis.
Species
Arabidopsis thaliana
Periplocin suppresses the growth of colorectal cancer cells by triggering LGALS3 (galectin 3)-mediated lysophagy
The interaction between STING and NCOA4 exacerbates lethal sepsis by orchestrating ferroptosis and inflammatory responses in macrophages - PMC
Journal
Cell death & disease
Ascorbate inducible N259 glycans on prolyl 4-hydroxylase subunit α1 promote hydroxylation and secretion of type I collagen.
Journal
Cellular and molecular life sciences
DDX5 inhibits inflammation by modulating m6A levels of TLR2/4 transcripts during bacterial infection
Structural Basis of VSIG3: The Ligand for VISTA
Host MKRN1-Mediated Mycobacterial PPE Protein Ubiquitination Suppresses Innate Immune Response
Journal
Frontiers in immunology
PIMT is a novel and potent suppressor of endothelial activation - PMC
PAQR9 regulates hepatic ketogenesis and fatty acid oxidation during fasting via modulating protein stability of PPAR
Protist ubiquitin ligase effector PbE3-2 targets cysteine protease RD21A to impede plant immunity
Domesticated HERV-W env contributes to the activation of the small conductance Ca2+-activated K+ type 2 channels via decreased 5-HT4 receptor in recent …
Interaction of NEP with G Protein Pathway Suppressor 2 Facilitates Influenza A Virus Replication by Weakening the Inhibition of GPS2 to RNA Synthesis and Ribonucleoprotein Assembly
Murine double minute 2 aggravates adipose tissue dysfunction through ubiquitin-mediated six-transmembrane epithelial antigen of prostate 4 degradation - PMC
ARIH1 inhibits influenza A virus replication and facilitates RIG-I dependent immune signaling by interacting with SQSTM1/p62 - PMC
MORC4 plays a tumor-promoting role in colorectal cancer via regulating PCGF1/CDKN1A axis in vitro and in vivo
Journal
Cancer gene therapy
Enhanced acetylation of ATP-citrate lyase promotes the progression of nonalcoholic fatty liver disease.
Journal
The Journal of biological chemistry
MicroRNA miR-722 Inhibits Cyprinid Herpesvirus 3 Replication via Targeting the Viral Immune Evasion Protein ORF89, Which Negatively Regulates IFN by Degrading …
Journal
Journal of immunology (Baltimore, Md. : 1950)
Perilipin 5 alleviates HCV NS5A-induced lipotoxic injuries in liver.
Journal
Lipids in health and disease
Drafting Penicillium oxalicum calcineurin-CrzA pathway by combining the analysis of phenotype, transcriptome, and endogenous protein-protein interactions
Species
Penicillium oxalicum
KRAS G12D mutation eliminates reactive oxygen species through the Nrf2/CSE/H2S axis and contributes to pancreatic cancer growth - PMC
Journal
Acta biochimica et biophysica Sinica
c-MYC-USP49-BAG2 axis promotes proliferation and chemoresistance of colorectal cancer cells in vitro
Journal
Biochemical and biophysical research communications
Feedback loop regulation between viperin and viral hemorrhagic septicemia virus through competing protein degradation pathways - PMC
Journal
bioRxiv : the preprint server for biology
Tim-4 reprograms cholesterol metabolism to suppress antiviral innate immunity by disturbing the Insig1-SCAP interaction in macrophages