Aberrant m5C hypermethylation mediates intrinsic resistance to gefitinib through NSUN2/YBX1/QSOX1 axis in EGFR-mutant non-small-cell lung cancer - PMC
Ectopic expression of human TUBB8 leads to increased aneuploidy in mouse oocytes - PMC
Structural insights into a shared mechanism of human STING activation by a potent agonist and an autoimmune disease-associated mutation - PMC
Protein arginine methyltransferase 5 mediates arginine symmetric dimethylation of influenza A virus PB2 and supports viral replication
Journal
Journal of medical virology
Genetically engineered M2-like macrophage-derived exosomes for P. gingivalis-suppressed cementum regeneration: From mechanism to therapy - PMC
Journal
Bioactive materials
Haploid-genetic screening of trophectoderm specification identifies Dyrk1a as a repressor of totipotent-like status - PMC
Exposure to Real-Ambient Particulate Matter Induced Vascular Hypertrophy by Activation of PDGFR
Journal
Journal of hazardous materials
Daucosterol confers protection against T-2 toxin induced blood-brain barrier toxicity through the PGC-1-mediated defensive response in vitro and in vivo
Journal
Journal of hazardous materials
VCAM-1-binding peptide targeted cationic liposomes containing NLRP3 siRNA to modulate LDL transcytosis as a novel therapy for experimental atherosclerosis
Journal
Metabolism: clinical and experimental
Low-Dose Deoxynivalenol Exposure Inhibits Hepatic Mitophagy and Hesperidin Reverses This Phenomenon by Activating SIRT1
Journal
Journal of hazardous materials
miR-4739 mediates pleural fibrosis by targeting bone morphogenetic protein 7.
Species
Homo sapiens, Mus musculus
Zwitterion‐Driven Shape Program of Prodrug Nanoassemblies with High Stability, High Tumor Accumulation, and High Antitumor Activity
Journal
Advanced healthcare materials
Melatonin-loaded self-healing hydrogel targets mitochondrial energy metabolism and promotes annulus fibrosus regeneration - PMC
Journal
Materials today. Bio
FOXA3 regulates cholesterol metabolism to compensate for low uptake during the progression of lung adenocarcinoma - PMC
Lipid droplets contribute myogenic differentiation in C2C12 by promoting the remodeling of the acstin-filament
Neoteric Semiembedded -Tricalcium Phosphate Promotes Osteogenic Differentiation of Mesenchymal Stem Cells under Cyclic Stretch
Journal
ACS applied materials & interfaces
Vascular Endothelial Growth Factor A Contributes to Increased Mammalian Respiratory Epithelial Permeability Induced by Pasteurella multocida Infection - PMC
Journal
Microbiology spectrum
Environment relevant exposure of perfluorooctanoic acid accelerates the growth of hepatocellular carcinoma cells through mammalian target of rapamycin (mTOR)
Journal
Environmental pollution (Barking, Essex : 1987)
Cytokine Secretion and Pyroptosis of Thyroid Follicular Cells Mediated by Enhanced NLRP3, NLRP1, NLRC4, and AIM2 Inflammasomes Are Associated With Autoimmune Thyroiditis
Journal
Frontiers in immunology
A bioenergeticallyactive ploy (glycerol sebacate)based multiblock hydrogel improved diabetic wound healing through revitalizing mitochondrial metabolism
Journal
Cell proliferation
Antigenicity, epitope mapping, and intracellular distribution of the NSP7 protein of porcine reproductive and respiratory syndrome virus
Journal
International journal of biological macromolecules
Janus silk fibroin/polycaprolactone-based scaffold with directionally aligned fibers and porous structure for bone regeneration
Journal
International journal of biological macromolecules
MORN4 protects cardiomyocytes against ischemic injury via MFN2-mediated mitochondrial dynamics and mitophagy
Journal
Free radical biology & medicine
Species
Rattus norvegicus,Mus musculus,Homo sapiens
BMSC-derived exosomes promote tendon-bone healing after anterior cruciate ligament reconstruction by regulating M1/M2 macrophage polarization in rats - PMC
Journal
Stem cell research & therapy
Species
Oryctolagus cuniculus
The effect of lncRNA MIR155HG-modified MSCs and exosome delivery to synergistically attenuate vein graft intimal hyperplasia - PMC
Journal
Stem cell research & therapy
KAP1 phosphorylation promotes the survival of neural stem cells after ischemia/reperfusion by maintaining the stability of PCNA - PMC
Journal
Stem cell research & therapy
Expression characteristics of non-virion protein of Hirame novirhabdovirus and its transfection induced response in hirame natural embryo cells
Journal
International journal of biological macromolecules
JunD functions as a transcription factor of IL-10 to regulate bacterial infectious inflammation in grass carp (Ctenopharyngodon idella)
Journal
International journal of biological macromolecules
Species
Ctenopharyngodon idellus
Mitotic defects lead to unreduced sperm formation in cdk1−/− mutants
Journal
International journal of biological macromolecules
Species
Misgurnus anguillicaudatus
Disc regeneration by injectable fucoidan-methacrylated dextran
hydrogels through mechanical transduction and macrophage
immunomodulation - PMC
Journal
Journal of tissue engineering
Circadian gene CSNK1D promoted the progression of hepatocellular carcinoma by activating Wnt/-catenin pathway via stabilizing Dishevelled Segment Polarity Protein 3 - PMC
Journal
Biological procedures online
miR-135a Suppresses Granulosa Cell Growth by Targeting Tgfbr1 and Ccnd2 during Folliculogenesis in Mice
Development of a Lung Vacancy Mouse Model through CRISPR/Cas9-Mediated Deletion of Thyroid Transcription Factor 1 Exon 2 - PMC
MITA oligomerization upon viral infection is dependent on its N-glycosylation mediated by DDOST - PMC
Species
Homo sapiens, Mus musculus
Immune checkpoint programmed death-1 mediates abdominal aortic aneurysm and pseudoaneurysm progression
Journal
Biomed Pharmacother
FoxO1 is a negative regulator of neointimal hyperplasia in a rat model of patch angioplasty
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Ephedra herb reduces adriamycin-induced testicular toxicity by upregulating the gonadotropin-releasing hormone signalling pathway
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Species
Oryctolagus cuniculus
GATA3 Exerts Distinct Transcriptional Functions to Regulate Radiation Resistance in A549 and H1299 Cells
Journal
Oxidative medicine and cellular longevity
Medulla oblongata and NCCs are central defenders against Streptococcus agalactiae infection of the tilapia brain - PMC
Journal
Frontiers in immunology
Paneth cells protect intestinal stem cell niche to alleviate deoxynivalenol-induced intestinal injury
Journal
Ecotoxicology and environmental safety
Deoxynivalenol exposure inhibits biosynthesis of milk fat and protein by impairing tight junction in bovine mammary epithelial cells
Journal
Ecotoxicology and environmental safety
Heparanase induces necroptosis of microvascular endothelial cells to promote the metastasis of hepatocellular carcinoma
Micro/Nanostructured Topography on Titanium Orchestrates Dendritic Cell Adhesion and Activation via 2 Integrin-FAK Signals - PMC
Journal
International journal of nanomedicine
Fbxo22 inhibits metastasis in triple-negative breast cancer through ubiquitin modification of KDM5A and regulation of H3K4me3 demethylation
Journal
Cell biology and toxicology
Total flavonoids of Selaginella tamariscina (P.Beauv.) Spring ameliorates doxorubicin-induced cardiotoxicity by modulating mitochondrial dysfunction and endoplasmic reticulum stress via activating MFN2/PERK
Journal
Phytomedicine : international journal of phytotherapy and phytopharmacology
Intestinal Flora Dysbiosis Aggravates Cognitive Dysfunction Associated With Neuroinflammation in Heart Failure
Journal
Journal of Cardiac Failure
Sodium New Houttuyfonate Induces Apoptosis of Breast Cancer Cells via ROS/PDK1/AKT/GSK3β Axis - PMC
EphA5 knockdown enhances the invasion and migration ability of esophageal squamous cell carcinoma via epithelial-mesenchymal transition through activating Wnt/β-catenin pathway
Journal
Cancer Cell International
The preventive effect and underlying mechanism of Rhus chinensis Mill. fruits on dextran sulphate sodium-induced ulcerative colitis in mice
Effects of Maternal High-Fructose Diet on Long Non-Coding RNAs and Anxiety-like Behaviors in Offspring - PMC
Journal
International journal of molecular sciences
Vasoactive Intestinal Peptide (VIP) Protects Nile Tilapia (Oreochromis niloticus) against Streptococcus agalatiae Infection - PMC
Journal
International journal of molecular sciences
Species
Oreochromis mossambicus
Unveiling the Potential of Nelumbo nucifera-Derived Liensinine to Target The Myostatin Protein and to Counteract Muscle Atrophy
Journal
Journal of agricultural and food chemistry
Grass carp reovirus VP56 and VP35 induce formation of viral inclusion bodies for replication - PMC
Species origin of exogenous transcription factors affects the activation of endogenous pluripotency markers and signaling pathways of porcine induced pluripotent stem cells - PMC
Journal
Frontiers in cell and developmental biology
Species
Sus scrofa,Bos taurus,Mus musculus
Engineered three-dimensional bioactive scaffold for enhanced bone regeneration through modulating transplanted adipose derived mesenchymal stem cell and stimulating angiogenesis - PMC
Journal
Frontiers in bioengineering and biotechnology
Egg Shell Membrane as an Alternative Vascular Patch for Arterial Angioplasty
Journal
Frontiers in bioengineering and biotechnology
Reperfusion after hypoxia-ischemia exacerbates brain injury with compensatory activation of the anti-ferroptosis system: based on a novel rat model
Journal
Neural regeneration research
A novel DEAH-box helicase 37 mutation associated with differences of sex development - PMC
Journal
Frontiers in endocrinology
Qiangji Decoction Alleviates Neurodegenerative Changes and Hippocampal Neuron Apoptosis Induced by D-Galactose via Regulating AMPK/SIRT1/NF-κB Signaling Pathway
Taohong siwu decoction attenuates AIM2 and NLRC4 inflammasomes by ameliorates deoxyribonucleic acid damage after ischemic stroke - PMC
Journal
Frontiers in pharmacology
Impairment of Pol-related DNA base-excision repair leads to ovarian aging in mice
Erythritol Improves Nonalcoholic Fatty Liver Disease by Activating Nrf2 Antioxidant Capacity
IGJ suppresses breast cancer growth and metastasis by inhibiting EMT via the NFB signaling pathway
Journal
International journal of oncology
GPA peptide enhances Nur77 expression in intestinal epithelial cells to exert a 1 protective effect against DSS-induced colitis
Zoledronic acid promotes TLR-4-mediated M1 macrophage polarization in bisphosphonate-related osteonecrosis of the jaw.
RNA m6A reader IGF2BP3 promotes metastasis of triple‐negative breast cancer via SLIT2 repression
Journal
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Impact of reduced apolipoprotein AI levels on pulmonary arterial hypertension
Journal
Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese
Species
Oryctolagus cuniculus
Baihe Extracts Reduce the Activation and Apoptosis of Microglia in the Hippocampus of Mice with Depression-like Behaviors by Downregulating MYC
Journal
ACS chemical neuroscience
Klebsiella pneumoniae outer membrane vesicles induce strong IL-8 expression via NF-B activation in normal pulmonary bronchial cells
Journal
International immunopharmacology
USF1 transcriptionally activates USP14 to drive atherosclerosis by promoting EndMT through NLRC5/Smad2/3 axis - PMC
Journal
Molecular medicine (Cambridge, Mass.)
Species
Homo sapiens,Mus musculus
Isobavachalcone's Alleviation of Pyroptosis Contributes to Enhanced Apoptosis in Glioblastoma: Possible Involvement of NLRP3
Journal
Molecular neurobiology
Acetate Alleviates Gut Microbiota Depletion-Induced Retardation of Skeletal Muscle Growth and Development in Young Mice - PMC
Journal
International journal of molecular sciences
Exosomes Derived from Adipose Mesenchymal Stem Cells Promote Regeneration of Injured Liver in Minipigs - PMC
Journal
International journal of molecular sciences
Vascular Endothelial Cell-Derived Exosomal Sphingosylphosphorylcholine Attenuates Myocardial IschemiaReperfusion Injury through NR4A2-Mediated
Journal
International journal of molecular sciences
Species
Homo sapiens,Rattus norvegicus
GAPDH Is a Novel Ferroptosis-Related Marker and Correlates with Immune Microenvironment in Lung Adenocarcinoma - PMC
Deoxynivalenol upregulates hypoxia-inducible factor-1 to promote an "immune evasion" process by activating STAT3 signaling
Journal
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Melatonin alleviates BDE-209-induced cognitive impairment and hippocampal neuroinflammation by modulating microglia polarization via SIRT1-mediated HMGB1 …
Journal
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Novel Metabolites from the Marine-Derived Fungus Peniophora sp. SCSIO41203 Show Promising In Vitro Antitumor Activity as Methuosis Inducers in PC-3 Cells - PMC
A novel rat model of vertebral inflammation-induced intervertebral disc degeneration mediated by activating cGAS/STING molecular pathway
Long non-coding RNA MALAT1 regulates angiogenesis following oxygen-glucose deprivation/reoxygenation.
Journal
Journal of Cellular and Molecular Medicine
Bufotalin enhances apoptosis and TMZ chemosensitivity of glioblastoma cells by promoting mitochondrial dysfunction via AKT signaling pathway - PMC
Isorhynchophylline ameliorates the progression of osteoarthritis by inhibiting the NF-B pathway
Journal
European journal of pharmacology
The role and mechanism of TGF-1 in the antidepressant-like effects of tetrahydrocurcumin
Journal
European journal of pharmacology
Effects and mechanisms of trifluridine alone or in combination with cryptotanshinone in inhibiting malignant biological behavior of gastric cancer
Journal
Cell cycle (Georgetown, Tex.)
Injectable Hydrogel Combined with Nucleus Pulposus-Derived Mesenchymal Stem Cells for the Treatment of Degenerative Intervertebral Disc in Rats
Journal
Stem Cells International
Cellular uptake of extracellular nucleosomes induces innate immune responses by binding and activating cGMP-AMP synthase (cGAS)
Pharmacological targeting of BET proteins attenuates radiation-induced lung fibrosis
Journal
Scientific Reports
Nrf2-mediated redox balance alleviates LPS-induced vascular endothelial cell inflammation by inhibiting endothelial cell ferroptosis - PMC
Journal
Scientific reports
ZNF143 facilitates the growth and migration of glioma cells by regulating KPNA2-mediated Hippo signalling - PMC
Journal
Scientific reports
Phenolic Compounds from Mori Cortex Ameliorate Sodium Oleate-Induced Epithelial-Mesenchymal Transition and Fibrosis in NRK-52e Cells through CD36
Anti-Inflammatory Activity of Essential Oil from Zingiber ottensii Valeton in Animal Models - PMC
Journal
Molecules (Basel, Switzerland)
AMPK activator decelerates osteoarthritis development by inhibition of -catenin signaling in chondrocytes - PMC
Journal
Journal of orthopaedic translation
MYOD induced lnc-MEG3 promotes porcine satellite cell differentiation via interacting with DLST - PMC
Saturated fatty acid promotes calcification via suppressing SIRT6 expression in vascular smooth muscle cells
Journal
Journal of hypertension
Distribution and response strategies of non-specific cytotoxic cell receptor protein 1 in large yellow croaker
Journal
Fish & shellfish immunology
Multifunctional Exosomes Derived from M2 Macrophages with Enhanced Odontogenesis, Neurogenesis and Angiogenesis for Regenerative Endodontic Therapy: An In Vitro and In Vivo Investigation - PMC
The antidepressive mechanism of Longya Lilium combined with Fluoxetine in mice with depression-like behaviors - PMC
Journal
NPJ systems biology and applications
S-nitrosoglutathione reductase-dependent p65 denitrosation promotes osteoclastogenesis by facilitating recruitment of p65 to NFATc1 promoter
Chronic Polystyrene Microplastic Exposure Reduces Testosterone Levels in Mice through Mitochondrial Oxidative Stress and BAX/BCL2-Mediated Apoptosis - PMC
microRNA-31 inhibition partially ameliorates the deficiency of bone marrow stromal cells from cleidocranial dysplasia.
Journal
Journal of cellular biochemistry
Sphingosylphosphorylcholine ameliorates doxorubicin-induced cardiotoxicity in zebrafish and H9c2 cells by reducing excessive mitophagy and mitochondrial …
Journal
Toxicology and applied pharmacology
CBX7 Rejuvenates Late Passage Dental Pulp Stem Cells by Maintaining Stemness and Pro-angiogenic Ability
Journal
Tissue engineering and regenerative medicine
Pasteurella multocida activates apoptosis via the FAK-AKT-FOXO1 axis to cause pulmonary integrity loss, bacteremia, and eventually a cytokine storm - PMC
Journal
Veterinary research
Unmasking the dynamics of Mycoplasma gallisepticum: deciphering HD11 macrophage polarization for innovative infection control strategies
Platelet-rich plasma activates tendon-derived stem cells to promote regeneration of Achilles tendon rupture in rats
Journal
JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE
Indole-3-carboxaldehyde alleviates cisplatin-induced acute kidney injury in mice by improving mitochondrial dysfunction via PKA activation
Journal
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Pax2 is Essential for Proliferation and Osteogenic Differentiation of Mouse Mesenchymal Stem Cells via Runx2
Journal
Experimental cell research
Biomimetic Elastin Fiber Patch in Rat Aorta Angioplasty
Dihydroquercetin regulates HIF-1/AKT/NR2B signalling to improve impaired brain function in rats with metabolic syndrome - PMC
Pharmacological Regulation of Primary Cilium Formation Affects the Mechanosensitivity of Osteocytes
Probiotics alleviate cognitive dysfunction associated with neuroinflammation in cardiac surgery.
Journal
American Journal of Translational Research
3D sheep rumen epithelial structures driven from single cells in vitro - PMC
Journal
Veterinary research
Stage-, dose-, and course-dependent inhibition of prenatal amoxicillin exposure on fetal articular cartilage development in fetal mice
Journal
Toxicology and applied pharmacology
Pralatrexate mediates effective killing of gemcitabine-resistant pancreatic cancer: role of mTOR/4E-BP1 signal pathway - PMC
Intramural injection of pluronic gel loaded with drugs to alleviate arterial injury
Journal
Microvascular research
Paraquat-activated BV-2 microglia induces neuroinflammatory responses in the neuron model through NF-κB signaling pathway
Journal
Toxicology in vitro : an international journal published in association with BIBRA
Viperin_sv1 promotes RIG-I expression and suppresses SVCV replication through its radical SAM domain
Molecular cloning and characterization of a cDNA encoding extracellular signal-regulated kinase (ERK) from the blood clam Tegillarca granosa
Journal
Developmental and Comparative Immunology
Species
Tegillarca granosa
Tacrolimus reverses pemphigus vulgaris serum-induced depletion of desmoglein in HaCaT cells via inhibition of heat shock protein 27 phosphorylation - PMC
miR-657 Targets SRCIN1 via the Slug Pathway to Promote NSCLC Tumor Growth and EMT Induction - PMC
Expression and significance of histone methyltransferase SET domain containing 2 with histone H3 lysine 36 trimethylation in mouse hepatic oval cells differentiated into bile duct epithelial cells in vitro - PMC
Journal
Molecular medicine reports
Clinical evidence for elevated levels of caveolin-1 in circulation of patients with diabetic foot ulcers
Journal
Wound Repair Regen
Depletion of chop suppresses procedural apoptosis and enhances innate immunity in loach Misgurnus anguillicaudatus under ammonia nitrogen stress
Journal
Journal of animal science
Species
Cobitis taenia Linnaeus
Electroacupuncture Alleviates Neuroinflammation by Inhibiting the HMGB1 Signaling Pathway in Rats with Sepsis-Associated Encephalopathy - PMC
The construction and immunogenicity analyses of a recombinant pseudorabies virus with porcine circovirus type 3 capsid protein co-expression
α-Pyrones with glucose uptake-stimulatory activity from the twigs of Cryptocarya wrayi
Stefin B alleviates the gouty arthritis in mice by inducing the M2 polarization of macrophages
Journal
Naunyn-Schmiedeberg's archives of pharmacology
Silencing HE4 alleviates the renal fibrosis in lupus nephritis mice by regulating the C3/MMPs/prss axis
Journal
Naunyn-Schmiedeberg's archives of pharmacology
LOC102549726/miR-760-3p network is involved in the progression of ISO-induced pathological cardiomyocyte hypertrophy via endoplasmic reticulum stress
Journal
Journal of molecular histology
Soybean Bioactive Peptide Supplementation Affects the Intestinal Immune Antioxidant Function, Microbial Diversity, and Reproductive Organ Development in Roosters - PMC
Journal
Animals : an open access journal from MDPI
A novel homozygous mutation in ACTL7A leads to male infertility
Journal
Molecular genetics and genomics : MGG
Species
Oryctolagus cuniculus
Extract of bulbus of Fritillaria cirrhosa induces spindle multipolarity in human-derived colonic epithelial NCM460 cells through promoting centrosome fragmentation
Neddylation Inhibition Affects Early Embryonic Development by Disrupting Maternal-to-Zygotic Transition and Mitochondrial Function in Mice
Clinical and Functional Characterization of Novel AGL Variants in Two Families with Glycogen Storage Disease Type III - PMC
Journal
International journal of endocrinology
Effects and mechanism of Rictor interference in podocyte injury induced by high glucose - PMC
Journal
Experimental and therapeutic medicine
Fluorofenidone attenuates renal fibrosis by inhibiting lysosomal cathepsinmediated NLRP3 inflammasome activation
Journal
Experimental and therapeutic medicine
Japanese encephalitis virus induces apoptosis by activating the RIG-1 signaling pathway
Journal
Archives of virology
Anti-Inflammatory Effects of Gynura procumbens on RAW264.7 Cells via Regulation of the PI3K/Akt and MAPK Signaling Pathways
Journal
Evidence-based complementary and alternative medicine : eCAM
A Method to Isolate Human Dermal Microvascular Pericytes Without the Use of Magnetic Beads Sorting in Vitro
Interaction of influenza A virus NS1 and cytoskeleton scaffolding protein α-actinin 4
SPP1 promotes tumor progression in esophageal carcinoma by activating focal adhesion pathway - PMC
Journal
Journal of gastrointestinal oncology
Umbilical cord mesenchymal stem cells inhibited inflammation of bronchial epithelial cells by regulating Hedgehog pathway - PMC
Journal
European journal of histochemistry : EJH
Effects of testosterone on skin structure and factors related to androgen conversion and binding in Hetian sheep
Journal
Tropical animal health and production
Experimental study of slow-released Angiogenin by silicon micro-needle in improving blood support to multiple-territory perforator flaps in rats
Journal
Cellular and molecular biology (Noisy-le-Grand, France)
Custom-designed, mass silk production in genetically engineered silkworms
Effect of bone-shaped nanotube-hydrogel drug delivery system for enhanced osseointegration
Journal
Biomaterials advances
Pseudoephedrine Nanoparticles Alleviate Adriamycin-Induced Reproductive Toxicity Through the GnRhR Signaling Pathway
Journal
International journal of nanomedicine