AEP-cleaved DDX3X induces alternative RNA splicing events to mediate cancer cell adaptation in harsh microenvironments - PMC
Journal
The Journal of clinical investigation
Targeting adipocyte ESRRA promotes osteogenesis and vascular formation in adipocyte-rich bone marrow - PMC
Journal
Nature communications
Ascorbate inducible N259 glycans on prolyl 4-hydroxylase subunit α1 promote hydroxylation and secretion of type I collagen.
Journal
Cellular and molecular life sciences
The regulation of MFGE8 on the mitophagy in diabetic sarcopenia via the HSPA1LParkin pathway and the effect of Dpinitol
Journal
Journal of cachexia, sarcopenia and muscle
BLK positively regulates TLR/IL-1R signaling by catalyzing TOLLIP phosphorylation
Journal
The Journal of cell biology
The Cdc42 GAP Rga6 promotes monopolar outgrowth of spores
Journal
The Journal of cell biology
Species
Saccharomyces cerevisiae
LncDGAT2 is a novel positive regulator of the goat adipocyte thermogenic gene program
Journal
International journal of biological macromolecules
Acute exposure of microwave impairs attention process by activating microglial inflammation - PMC
An Antibody-directed and Immune Response Modifier-augmented Photothermal Therapy Strategy Relieves Aging via Rapid Immune Clearance of Senescent Cells - PMC
miR-145a-5p/Plexin-A2 promotes the migration of OECs and transplantation of miR-145a-5p engineered OECs promotes the functional recovery in rats with …
Journal
Neurobiology of disease
HDAC9 Deficiency Upregulates cGMP-dependent Kinase II to Mitigate Neuronal Apoptosis in Ischemic Stroke
Journal
Translational stroke research
Intestinal metabolite UroB alleviates cerebral ischemia/reperfusion injury by promoting competition between TRIM65 and TXNIP for binding to NLRP3 inflammasome
Journal
Biochimica et biophysica acta. Molecular basis of disease
Intestinal metabolite UroB alleviates cerebral ischemia/reperfusion injury by promoting competition between TRIM65 and TXNIP for binding to NLRP3 inflammasome
Journal
Biochimica et biophysica acta. Molecular basis of disease
Borneol-modified PEGylated graphene oxide as a nanocarrier for brain-targeted delivery of ginsenoside Rg1 against depression
Journal
International journal of pharmaceutics
Isobutyric acid promotes colorectal cancer metastasis through activating RACK1
Nanoscale metal-organic framework delivers rapamycin to induce tissue immunogenic cell death and potentiates cancer immunotherapy
Journal
Nanomedicine : nanotechnology, biology, and medicine
EGFR suppression contributes to growth inhibitory activity of G-quadruplex ligands in non-small cell lung cancers
Journal
Biochemical pharmacology
SARS-CoV-2 Nsp15 suppresses type I interferon production by inhibiting IRF3 phosphorylation and nuclear translocation - PMC
Bixin protects mice against bronchial asthma though modulating PI3K/Akt pathway
Journal
Int Immunopharmacol
Caspase-8 is involved in pyroptosis, necroptosis and the maturation and release of IL-1β in Aspergillus fumigatus keratitis
Journal
International immunopharmacology
sVCAM1 in the Hippocampus Contributes to Postoperative Cognitive Dysfunction in Mice by Inducing Microglial Activation Through the VLA-4 Receptor
Journal
Molecular neurobiology
Haemophilus parasuis α-2,3-sialyltransferase-mediated lipooligosaccharide sialylation contributes to bacterial pathogenicity.
Species
Haemophilus parasuis
GCRV-II invades monocytes/macrophages and induces macrophage polarization and apoptosis in tissues to facilitate viral replication and dissemination
Journal
Journal of virology
A Biflavonoid-Rich Extract from Selaginella doederleinii Hieron. against Throat Carcinoma via Akt/Bad and IKKβ/NF-κB/COX-2 Pathways - PMC
Journal
Pharmaceuticals (Basel, Switzerland)
Salidroside, a phenyl ethanol glycoside from Rhodiola crenulata, orchestrates hypoxic mitochondrial dynamics homeostasis by stimulating Sirt1/p53/Drp1 signaling
Journal
Journal of ethnopharmacology
Tangeretin and 4-demethyltangeretin prevent damage to mouse hepatocytes from oxidative stress by activating the Nrf2-related antioxidant pathway via an
Journal
Chemico-biological interactions
Lentinan improves intestinal inflammation and gut dysbiosis in antibiotics-induced mice - PMC
Journal
Scientific reports
TMT-Based Proteomics Reveal the Mechanism of Action of Amygdalin against Rheumatoid Arthritis in a Rat Model through Regulation of Complement and Coagulation Cascades - PMC
Journal
Molecules (Basel, Switzerland)
Species
Oryctolagus cuniculus
Effects of OsRCA Overexpression on Rubisco Activation State and Photosynthesis in Maize - PMC
Journal
Plants (Basel, Switzerland)
Polysaccharide of Atractylodes macrocephala Koidz (PAMK) protects against DEHP-induced apoptosis in grass carp hepatocytes
Journal
Fish & shellfish immunology
Species
Ctenopharyngodon idellus
Plasma Concentrations of High Mobility Group Box 1 Proteins and Soluble Receptors for Advanced Glycation End-Products Are Relevant Biomarkers of Cognitive Impairment in Alcohol Use Disorder: A Pilot Study - PMC
Female-specific activation of pregnane X receptor mediates sex difference in fetal hepatotoxicity by prenatal monocrotaline exposure
Journal
Toxicol Appl Pharmacol
Amphetamine-induced Neurite Injury in PC12 Cells Through Inhibiting GAP-43 Pathway
Delivery of microRNA-423-5p by exosome from adipose-derived stem/stromal cells inhibits DVL3 to potentiate autologous fat graft survival through adipogenesis and
Overexpressed lncRNA FTX promotes the cell viability, proliferation, migration and invasion of renal cell carcinoma via FTX/miR-4429/UBE2C axis - PMC
Giardia duodenalis induces extrinsic pathway of apoptosis in intestinal epithelial cells through activation of TNFR1 and K63 de-ubiquitination of RIP1 in vitro
The characterization of hematopoietic tissue in adult Chinese mitten crab Eriocheir sinensis
Journal
Developmental And Comparative Immunology
miR-743b-3p promotes hepatic lipogenesis via branched-chain amino acids (BCAA) metabolism by targeting PPM1K in aged mice
Journal
Archives of gerontology and geriatrics
Estrogen 17β‑estradiol accelerates the proliferation of uterine junctional zone smooth muscle cells via the let‑7a/Lin28B axis in adenomyosis
Journal
Molecular medicine reports
Angiotensin-(1-7) suppresses airway inflammation and airway remodeling via inhibiting ATG5 in allergic asthma - PMC
Journal
BMC pulmonary medicine
Species
Oryctolagus cuniculus
Metabotropic Glutamate Receptor 5 Blockade Attenuates Pathological Cardiac Remodeling in Pulmonary Arterial Hypertension
Journal
Clinical and experimental pharmacology & physiology
Innovative Fusion: Natural CompoundRhein and PROTACs Unleash Potent VEGFR2 Degraders
Journal
Chemistry & biodiversity
miR-146b-5p activation of hepatic stellate cells contributes to the progression of fibrosis by directly targeting HIPK1 - PMC
Journal
Experimental and therapeutic medicine
Protein Disulfide Isomerase A2 Is Correlated with Immune Infiltrates and Is a Novel Prognostic Biomarker in Glioma Patients
Journal
Current medical science
miR-181c, a potential mediator for acute kidney injury in a burn rat model with following sepsis
Journal
European journal of trauma and emergency surgery : official publication of the European Trauma Society
Protective effects of orientin against spinal cord injury in rats
NFYC-37 promotes tumor growth by activating the mevalonate pathway in bladder cancer
Application
WB, Co-IP, RT-PCR
Species
Homo sapiens, Mus musculus
Phosphorylation of Bub1 by Mph1 promotes the Bub1 signaling at the kinetochore to ensure accurate chromosome segregation
Journal
The Journal of biological chemistry
Species
Saccharomyces cerevisiae
HECTD3 inhibits NLRP3 inflammasome assembly and activation by blocking NLRP3-NEK7 interaction - PMC
Journal
Cell death & disease
A KDELR-mediated ER-retrieval system modulates mitochondrial functions via the unfolded protein response in fission yeast
Journal
The Journal of biological chemistry
ENPP1 ameliorates vascular calcification via inhibiting the osteogenic transformation of VSMCs and generating PPi - PMC
Journal
Open medicine (Warsaw, Poland)