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Biotinylated Rabbit anti-Human IL-2 mAb (RM17590B)

No significant cross-reactivity or interference was observed.

This standard curve is only for demonstration purposes. A standard curve should be generated for eachassay.

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货号: RM17590B
价 格:  29525.00
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详细信息

RM17590B
Biotinylated Rabbit anti-Human IL-2 mAb
样本类型
Supplied as a 0.2 μm filtered solution in PBS with 0.05% Proclin 300, pH 7.4.
反应时间
Human
检测范围
Recombinant IL-2 Protein
组分
Secreted.
储存条件
Store at -20℃
安全说明
No cross-reactivity in immunoassay with recombinant
hG-CSF, hGM-CSF, hIL-1α, hIL-1β, hIL-2R, hIL-3, hIL-4, hIL-6, hIL-8, hTGF-β1, hTNF-α, mIL-1β, mIL-2, mIL-6, mIL-4, mIL-5, mIL-2
For research purposes only. Not for therapeutic or diagnostic purposes in humans or animals.

* This package insert must be read in its entirety before using this product.

背景信息

This gene is a member of the interleukin 2 (IL2) cytokine subfamily which includes IL4, IL7, IL9, IL15, IL21, erythropoietin, and thrombopoietin. The protein encoded by this gene is a secreted cytokine produced by activated CD4+ and CD8+ T lymphocytes, that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine (IL2R) is a heterotrimeric protein complex whose gamma chain is also shared by IL4 and IL7. The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.