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Rabbit anti-Human IL-6 mAb (CAP) (RM17629)

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货号: RM17629
促销价：   ￥1260
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详细信息

产品名称
Rabbit anti-Human IL-6 mAb (CAP)
货号
RM17629
免疫原
E. coli-derived human IL-6 protein
Pro29-Met212
Accession #Q75MH2
纯化方式
Affinity purification
同种型
Rabbit IgG
存储溶液
Supplied as a 0.2um filtered solution in PBS with 0.1%Braveds MB-1,PH 7.4.
CrossReactivity
No cross-reactivity in ELISA and WB with
Recombinant human CNTF、IL-2 、IL-3、G-CSF、 IL-4 、M-CSF、IL-5 、IL-1A、IL-1B 、IL-6RA、IL-6RB、IL-7、IL-8&Recombinant mouse IL-6、IL-2、IL-4、IL-11、 IL-12
存储条件
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free.Avoid repeated freeze-thaw cycles.

* This package insert must be read in its entirety before using this product.

背景信息

Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway (Probable). The interaction with the membrane-bound IL6R and IL6ST stimulates ‘‘classic signaling’‘, whereas the binding of IL6 and soluble IL6R to IL6ST stimulates ‘‘trans-signaling’‘. Alternatively, ‘‘cluster signaling’‘ occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells (Probable).

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