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Rabbit anti-Human CRP mAb (CAP) (RM17641)

货号: RM17641
促销价:   ¥2100
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详细信息

产品名称
Rabbit anti-Human CRP mAb (CAP)
货号
RM17641
免疫原
Recombinant Human CRP Protein
Phe17-Pro224
Accession #P02741
纯化方式
Affinity purification
同种型
Rabbit IgG
存储溶液
Supplied as a 0.2um filtered solution in PBS with 0.1%Braveds MB-1,PH 7.4.
CrossReactivity
No cross-reactivity in ELISA with recombinant
hFicolin-1,rCRP,mCRP
存储条件
Store at -20℃. Avoid freeze / thaw cycles. Preservative:0.05%ProClin 300.Avoid repeated freeze-thaw cycles.

* This package insert must be read in its entirety before using this product.

应用

Human CRP Sanwich ELISA Immunoassay

 Recommended
Concentration
Sample
ELISA Capture0.5-2ug/mLHuman CRP Monoclonal Antibody, Rabbit MAb(CAP)(Cat. No. RM17641)
ELISA Detection0.05-0.2ug/mLHuman CRP Monoclonal Antibody, Rabbit MAb(DET)(Cat. No. RM17642)
Standard39-2500pg/mLRecombinant Human CRP Protein(Cat. No. RM00337)

背景信息

The protein encoded by this gene belongs to the pentraxin family which also includes serum amyloid P component protein and pentraxin 3. Pentraxins are involved in complement activation and amplification via communication with complement initiation pattern recognition molecules, but also complement regulation via recruitment of complement regulators. The encoded protein has a calcium dependent ligand binding domain with a distinctive flattened beta-jellyroll structure. It exists in two forms as either a pentamer in circulation or as a nonsoluble monomer in tissues. It is involved in several host defense related functions based on its ability to recognize foreign pathogens and damaged cells of the host and to initiate their elimination by interacting with humoral and cellular effector systems in the blood. Consequently, the level of this protein in plasma increases greatly during acute phase response to tissue injury, infection, or other inflammatory stimuli. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection.

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