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Rabbit anti-Human IL-5 mAb (CAP) (RM17737)

This standard curve is only for demonstration purposes. A standard curve should be generated for eachassay.

No significant cross-reactivity or interference was observed.

No significant cross-reactivity or interference was observed.

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货号: RM17737
促销价:   ¥2100
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详细信息

产品名称
Rabbit anti-Human IL-5 mAb (CAP)
货号
RM17737
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 20-134 of human IL-5 (NP_000870.1).
纯化方式
Affinity purification
同种型
Rabbit IgG
存储溶液
Supplied as a 0.2μm filtered solution in PBS with 0.05% Proclin300, PH 7.4.
CrossReactivity
No cross-reactivity in ELISA with recombinant
hIL-2、hIL-3、hIL-4、hIL-9、mIL-5、mIL-2、mIL-4、mIL-9、Human GM-CSF、mGM-CSF、rGM-CSF
存储条件
Store at -20℃.Avoid repeated freeze-thaw cycles.

* This package insert must be read in its entirety before using this product.

应用

Human IL-5 Sanwich ELISA Immunoassay

 Recommended
Concentration
Sample
ELISA Capture1-4ug/mLRabbit anti-Human IL-5 mAb (CAP) (Cat. No.RM17737)
ELISA Detection0.04-0.16ug/mLRabbit anti-Human IL-5 mAb (DET (Cat. No.RM17738)
Standard1.56-100pg/mLRabbit anti-Human IL-5 Protein

背景信息

This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.

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