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Human CD63 Sanwich ELISA Immunoassay
Recommended Concentration | Sample | |
---|---|---|
ELISA Capture | 1-4ug/mL | Rabbit anti-Human CD63(CAP)(Cat. No.RM17774) |
ELISA Detection | 0.075-0.3ug/mL | Rabbit anti-Human CD63(DET)(Cat. No.RM17775) |
Standard | 78-5000pg/mL | Recombinant Human CD63 Protein |
Functions as cell surface receptor for TIMP1 and plays a role in the activation of cellular signaling cascades. Plays a role in the activation of ITGB1 and integrin signaling, leading to the activation of AKT, FAK/PTK2 and MAP kinases. Promotes cell survival, reorganization of the actin cytoskeleton, cell adhesion, spreading and migration, via its role in the activation of AKT and FAK/PTK2. Plays a role in VEGFA signaling via its role in regulating the internalization of KDR/VEGFR2. Plays a role in intracellular vesicular transport processes, and is required for normal trafficking of the PMEL luminal domain that is essential for the development and maturation of melanocytes. Plays a role in the adhesion of leukocytes onto endothelial cells via its role in the regulation of SELP trafficking. May play a role in mast cell degranulation in response to Ms4a2/FceRI stimulation, but not in mast cell degranulation in response to other stimuli.