产品和服务 / 产品类型 / ELISA试剂盒 / ELISA 抗体对

Rabbit anti-Human sST2 mAb (RM17779)

This standard curve is only for demonstration purposes. A standard curve should be generated for eachassay.

Fromthe comparison of the standard curve, it is found that ABclonal has highsensitivity.

No significant cross-reactivity or interference was observed.

Placed at 37°C for 3 days, the stability of the standard curve all conformto CV <10%.

All(4)|
货号: RM17779
促销价:   ¥2100
抗体定制
服务咨询
|
扫码下单
享受积分

详细信息

产品名称
Rabbit anti-Human sST2 mAb
货号
RM17779
免疫原
Recombinant Human sST2 Protein
纯化方式
Affinity purification
同种型
Rabbit IgG
存储溶液
Supplied as a 0.2μm filtered solution in PBS with 0.05% Proclin300, PH 7.4.
CrossReactivity
No significant cross-reactivity or interference between sST2 and analogues was observed.
存储条件
Store at -20℃.Avoid repeated freeze-thaw cycles.

* This package insert must be read in its entirety before using this product.

应用

Human sST2 Sandwich Immunoassay

  Recommended
Concentration
Sample
ELISACapture1-4ug/mLRabbit anti-Human sST2 mAb(Cat. No.RM17778)
Detection0.015-0.06ug/mLRabbit anti-Human sST2 mAb(Cat. No.RM17779)
Standard7.8-500pg/mLRecombinant Human sST2 Protein

背景信息

Receptor for somatostatin-14 and -28. This receptor is coupled via pertussis toxin sensitive G proteins to inhibition of adenylyl cyclase. In addition it stimulates phosphotyrosine phosphatase and PLC via pertussis toxin insensitive as well as sensitive G proteins. Inhibits calcium entry by suppressing voltage-dependent calcium channels. Acts as the functionally dominant somatostatin receptor in pancreatic alpha- and beta-cells where it mediates the inhibitory effect of somatostatin-14 on hormone secretion. Inhibits cell growth through enhancement of MAPK1 and MAPK2 phosphorylation and subsequent up-regulation of CDKN1B. Stimulates neuronal migration and axon outgrowth and may participate in neuron development and maturation during brain development. Mediates negative regulation of insulin receptor signaling through PTPN6. Inactivates SSTR3 receptor function following heterodimerization