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This standard curve is only for demonstration purposes. A standard curve should be generated for eachassay.
Fromthe comparison of the standard curve, it is found that ABclonal has highsensitivity.
Placed at 37°C for 3 days, the stability of the standard curve all conformto CV <10%.
* This package insert must be read in its entirety before using this product.
Human MMP3 Sandwich ELISA Immunoassay
| Recommended Concentration | Sample | |
|---|---|---|
| ELISA Capture | 1-4ug/mL | Rabbit anti-Human MMP3(CAP)(Cat. No.RM17819) |
| ELISA Detection | 0.02-0.08ug/mL | Rabbit anti-Human MMP3(DET)(Cat. No.RM17820) |
| Standard | 0.467-30ng/mL | Recombinant Human MMP3 Protein(Cat. No.RP00220) |
Matrix metalloproteinases (MMP) are a family of proteases that target many extracellular proteins, including other proteases, growth factors, cell surface receptors, and adhesion molecules. Among these family members, MMP-2, MMP-3, MMP-7, and MMP-9 are considered important factors in normal tissue remodeling during embryonic development, injury repair, cancer invasion, angiogenesis, oncogenesis, and apoptosis. Studies have demonstrated that MMP activity is associated with cancer progression .One mechanism of MMP regulation is transcription (5). Once synthesized, MMP exists as an inactive zymogen. maximum MMP activity requires proteomic shearing, releasing the inhibitory pre-peptide structural domain from the full-length protein to form an active MMP
