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Human Cathepsin B Sanwich ELISA Immunoassay
Recommended Concentration | Sample | |
---|---|---|
ELISA Capture | 2-8ug/mL | Rabbit anti-Human Cathepsin B (CAP)(Cat. No.RM06897) |
ELISA Detection | 0.0006-0.0024ug/mL | Rabbit anti-Human Cathepsin B (DET)(Cat. No.RM06899) |
Standard | 0.31-20ng/mL | Recombinant Human Cathepsin B Protein |
Cathepsin B is the first described member of the family of lysosomal cysteine proteases. Cathepsin B possesses both endopeptidase and exopeptidase activities, in the latter case acting as a peptidyl-dipeptidase. It is known to process a number of proteins, including pro and active caspases, prorenin and SLPI. Cathepsin B is synthesized as a preproenzyme. Following removal of the signal peptide, the inactive proenzyme undergoes further modifications including removal of the pro region to result in the active enzyme