产品和服务 / 产品类型 / ELISA试剂盒 / ELISA 抗体对
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Human AFP Sandwich ELISA
Recommended Concentration | Sample | ||
---|---|---|---|
ELISA | Capture | 0.5-2ug/mL | Rabbit anti-Human AFP mAb(Cat. No.RM18023) |
Detection | 0.0083-0.0332ug/mL | Rabbit anti-Human AFP mAb(Cat. No.RM18024) | |
Standard | 0.15-10ng/mL | Recombinant Human Alpha-fetoprotein/AFP Protein |
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatocarcinoma and with teratoma, and has prognostic value for managing advanced gastric cancer. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.