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Rabbit anti-Human CCL2/MCP-1 mAb (RM18048)

This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

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货号: RM18048
促销价:   ¥2100
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详细信息

产品名称
Rabbit anti-Human CCL2/MCP-1 mAb
货号
RM18048
免疫原
Recombinant fusion protein containing a sequence corresponding to amino acids 22-99 of human CCL2/MCP-1 (NP_002973.1).
纯化方式
Affinity purification
同种型
Rabbit IgG
存储溶液
Supplied as a 0.2μm filtered solution in PBS with 0.05% Proclin300, PH 7.4.
存储条件
Store at -20℃. Avoid repeated freeze-thaw cycles.

* This package insert must be read in its entirety before using this product.

应用

Human CCL2/MCP-1 Sandwich Immunoassay

  Recommended
Concentration
Sample
MultiplexCapture3-20ug/mLRabbit anti-Human CCL2/MCP-1 mAb(CAP)(Cat. No.RM18047)
Detection0.017-2ug/mLRabbit anti-Human CCL2/MCP-1 mAb(DET)(Cat. No.RM18048)
Standard1.37-1000pg/mLRecombinant Human CCL2/MCP-1 Protein

背景信息

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of N-terminal cysteine residues of the mature peptide. This chemokine is a member of the CC subfamily which is characterized by two adjacent cysteine residues. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. Elevated expression of the encoded protein is associated with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection.

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