
产品和服务 / 产品类型 / ELISA试剂盒 / ELISA 抗体对
* This package insert must be read in its entirety before using this product.
Human GM-CSF Sandwich Immunoassay
| Recommended Concentration | Sample | |
|---|---|---|
| ELISA Capture | 1-4 μg/mL | Rabbit anti-Human GM-CSF mAb (Cat. No. RMK0105) |
| ELISA Detection | 0.033-0.132 μg/mL | Rabbit anti-Human GM-CSF mAb (Cat. No. RMK0107) |
| Standard | 7.81-500 pg/mL | Recombinant Human GM-CSF Protein |
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. This gene plays a role in promoting tissue inflammation. Elevated levels of cytokines, including the one produced by this gene, have been detected in SARS-CoV-2 infected patients that develop acute respiratory distress syndrome. Mice deficient in this gene or its receptor develop pulmonary alveolar proteinosis.