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Rabbit anti- Human TSLP mAb(DET) (RMK0114)

货号: RMK0114
促销价:   ¥2100
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详细信息

产品名称
Rabbit anti- Human TSLP mAb(DET)
货号
RMK0114
免疫原
Recombinant Human TSLP
纯化方式
Affinity purification
同种型
Rabbit IgG
存储溶液
Supplied as a 0.2um filtered solution in PBS with 0.05%ProClin 300,PH 7.4.
存储条件
Store at -20℃. Avoid freeze / thaw cycles. Preservative:0.05%ProClin 300.Avoid repeated freeze-thaw cycles.

* This package insert must be read in its entirety before using this product.

应用

Human TSLP Sandwich ELISA Immunoassay

 Recommended
Concentration
Sample
ELISA Capture1-4ug/mLRabbit anti-Human TSLP (CAP)(Cat. No.RMK0113)
ELISA Detection2.5-10ng/mLRabbit anti-Human TSLP (DET)(Cat. No.RMK0114)
Standard31.25-2000pg/mLRecombinant Human TSLP Protein(Cat. No.RP01172)

背景信息

This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. In addition, the shorter (predominant) isoform is an antimicrobial protein, displaying antibacterial and antifungal activity against B. cereus, E. coli, E. faecalis, S. mitis, S. epidermidis, and C. albicans. Alternative splicing of this gene results in multiple transcript variants.

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