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Rabbit anti- Human CA125/MUC16 mAb(DET) (RMK0181)

This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

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货号: RMK0181
促销价:   ¥2100
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详细信息

产品名称
Rabbit anti- Human CA125/MUC16 mAb(DET)
货号
RMK0181
免疫原
Recombinant Human CA125
纯化方式
Affinity purification
同种型
Rabbit IgG
存储溶液
Supplied as a 0.2um filtered solution in PBS with 0.05%ProClin 300,PH 7.4.
CrossReactivity
/
存储条件
Store at -20℃. Avoid freeze / thaw cycles. Preservative:0.05%ProClin 300.Avoid repeated freeze-thaw cycles.

* This package insert must be read in its entirety before using this product.

应用

Human CA125 Sandwich ELISA Immunoassay

 Recommended
Concentration
Sample
ELISA Capture0.5-2ug/mLRabbit anti-Human CA125 (CAP)(Cat. No.RMK0180)
ELISA Detection1.25-5ng/mLRabbit anti-Human CA125 (DET)(Cat. No.RMK0181)
Standard0.312-20U/mLRecombinant Human CA125 Protein

背景信息

This gene encodes a protein that is a member of the mucin family. Mucins are high molecular weight, O-glycosylated proteins that play an important role in forming a protective mucous barrier, and are found on the apical surfaces of the epithelia. The encoded protein is a membrane-tethered mucin that contains an extracellular domain at its amino terminus, a large tandem repeat domain, and a transmembrane domain with a short cytoplasmic domain. The amino terminus is highly glycosylated, while the repeat region contains 156 amino acid repeats unit that are rich in serines, threonines, and prolines. Interspersed within the repeats are Sea urchin sperm protein Enterokinase and Agrin (SEA) modules, leucine-rich repeats and ankyrin (ANK) repeats. These regions together form the ectodomain, and there is a potential cleavage site found near an SEA module close to the transmembrane domain. This protein is thought to play a role in forming a barrier, protecting epithelial cells from pathogens. Products of this gene have been used as a marker for different cancers, with higher expression levels associated with poorer outcomes.