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Human CA125 Sandwich ELISA Immunoassay
| Recommended Concentration | Sample | |
|---|---|---|
| ELISA Capture | 0.5-2ug/mL | Rabbit anti-Human CA125 (CAP)(Cat. No.RMK0180） |
| ELISA Detection | 1.25-5ng/mL | Rabbit anti-Human CA125 (DET)(Cat. No.RMK0181） |
| Standard | 0.312-20U/mL | Recombinant Human CA125 Protein |
The CA125 antigen, also known as MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. Expression of isoforms, proteolytic cleavage, and heavy N- and O- linked glycosylation produce forms of human CA125 that can vary from 200-5000 kDa in size. It inhibits NK cell activity, which is thought to contribute to immune evasion in peritoneal cancer and pregnancy.
