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Rabbit anti-Human Amyloid beta (1-42) mAb(CAP) (RMK0189)

This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

No significant cross-reactivity or interference was observed.

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货号: RMK0189
促销价:   ¥2100
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详细信息

产品名称
Rabbit anti-Human Amyloid beta (1-42) mAb(CAP)
货号
RMK0189
免疫原
A synthetic peptide corresponding to a sequence within amino acids 672-713 of human β-Amyloid 1-42(NP_000475.1).
纯化方式
Affinity purification
同种型
Rabbit IgG
存储溶液
Supplied as a 0.2um filtered solution in PBS with 0.05%ProClin 300,PH 7.4.
CrossReactivity
存储条件
Store at -20℃. Avoid repeated freeze-thaw cycles.

* This package insert must be read in its entirety before using this product.

应用

Human Amyloid beta (1-42) Sandwich Immunoassay

 Recommended
Concentration
Sample
Capture1-4ug/mLRabbit anti-Human Amyloid beta (1-42) mAb(Cat. No.RMK0189)
Detection0.033-0.13ug/mLRabbit anti-Human Amyloid beta mAb(Cat. No.RMK0217)
Standard7.8125-500pg/mLRecombinant Human Amyloid beta (1-42) Protein

背景信息

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are antimicrobial peptides, having been shown to have bacteriocidal and antifungal activities. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

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