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* This package insert must be read in its entirety before using this product.
Mouse IFN-β multiplex assay
| Recommended Concentration | Sample | |
|---|---|---|
| Multiplex Capture | 3-20ug/mL | Rabbit anti-Mouse IFN-β mAb(Cat. No.RMK0212) |
| Multiplex Detection | 0.017-2ug/mL | Rabbit anti-Mouse IFN-β mAb(Cat. No.RMK0213) |
| Standard | 6.86-5000pg/mL | Recombinant Mouse IFN-β Protein |
Interferon-beta (IFN-beta) is a cytokine that is produced by fibroblasts and pathogen-exposed dendritic cells, macrophages, and endothelial cells. It signals through the heterodimeric IFN-alpha/beta Receptor. IFN-beta-deficient mice show increased susceptibility to experimental autoimmune encephalomyelitis (EAE), a disease model of human multiple sclerosis (MS). Furthermore, IFN-beta has been shown to suppress the Th17 cell response in both MS and EAE and has commonly been used as a treatment for MS.
