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Mouse IL-17A multiplex assay
| Recommended Concentration | Sample | |
|---|---|---|
| Multiplex Capture | 3-20ug/mL | Rabbit anti-Mouse IL-17A mAb(Cat. No.RM17904) |
| Multiplex Detection | 0.017-2ug/mL | Rabbit anti-Mouse IL-17A mAb(Cat. No.RMK0214) |
| Standard | 6.86-5000pg/mL | Recombinant Mouse IL-17A Protein |
Interleukin‑17A (IL‑17A), also known as CTLA‑8, is a 15‑20 kDa glycosylated cytokine that plays an important role in anti‑microbial and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conserved cystine knot fold (1, 2). Mature mouse IL‑17A shares 61% and 89% amino acid sequence identity with human and rat IL‑17A, respectively (3, 4). IL‑17A is secreted by Th17 cells, gamma /δ T cells, iNKT cells, NK cells, LTi cells, neutrophils, and intestinal Paneth cells
