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Human B7-1/CD80 multiplex assay
| Recommended Concentration | Sample | |
|---|---|---|
| Multiplex Capture | 3-20ug/mL | Rabbit anti-Human B7-1/CD80 mAb(Cat. No.RM18039) |
| Multiplex Detection | 0.017-2ug/mL | Rabbit anti-Human B7-1/CD80 mAb(Cat. No.RMK0245) |
| Standard | 6.86-5000pg/mL | Recombinant Human B7-1/CD80 Protein |
B7-1 and B7-2, together with their receptors CD28 and CTLA-4, constitute one of the dominant co-stimulatory pathways that regulate T- and B-cell responses. Although both CTLA-4 and CD28 can bind to the same ligands, CTLA-4 binds to B7-1 and B7-2 with a 20-100 fold higher affinity than CD28 and is involved in the down‑regulation of the immune response.
