产品和服务 / 产品类型 / ELISA试剂盒 / ELISA 抗体对
* This package insert must be read in its entirety before using this product.
Human EPOR Sandwich Immunoassay
Recommended Concentration | Sample | |
---|---|---|
ELISA Capture | 1-4 μg/mL | Rabbit anti-Human EPOR mAb (Cat. No. RMK0270) |
ELISA Detection | 0.002-0.008 μg/mL | Rabbit anti-Human EPOR mAb (Cat. No. RMK0271) |
Standard | 31.25-2000 pg/mL | Recombinant Human Erythropoietin R/EPO-R Protein (Cat. No. RP00111) |
This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.