产品和服务 / 产品类型 / ELISA试剂盒 / ELISA 抗体对
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Human TRAIL-R3/CD263 multiplex assay
Recommended Concentration | Sample | |
---|---|---|
Multiplex Capture | 3-20ug/mL | Rabbit anti-Human TRAIL-R3/CD263 mAb(Cat. No.RMK0403) |
Multiplex Detection | 0.017-2ug/mL | Rabbit anti-Human TRAIL-R3/CD263 mAb(Cat. No.RMK0404) |
Standard | 6.86-5000pg/mL | Recombinant Human TRAIL-R3/CD263 Protein |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.