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Rabbit anti-Human TNF-alpha mAb (RMK0415)

This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

No significant cross-reactivity or interference was observed.

Placed at 37°C for 4 days, the stability of the standard curve all conform to CV <10%.

All(3)|
货号: RMK0415
促销价:   ¥2100
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详细信息

产品名称
Rabbit anti-Human TNF-alpha mAb
货号
RMK0415
免疫原
Recombinant Human TNF-alpha protein.
纯化方式
Affinity purification
同种型
Rabbit IgG
存储溶液
Supplied as a 0.2μm filtered solution in PBS with 0.05% Proclin300, PH 7.4.
CrossReactivity
/
存储条件
Store at -20℃. Avoid repeated freeze-thaw cycles.

* This package insert must be read in its entirety before using this product.

应用

Human TNF-alpha Sandwich Immunoassay

  Recommended
Concentration
Sample
ELISACapture1-4ug/mLRabbit anti-Human TNF-alpha mAb(Cat. No.RMK0415)
Detection0.125-0.5ug/mLRabbit anti-Human TNF-alpha mAb(Cat. No. RMK0416)
Standard0.78-50pg/mLRecombinantHuman TNF-alpha Protein(Cat. No. RP00001)

背景信息

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, psoriasis, rheumatoid arthritis ankylosing spondylitis, tuberculosis, autosomal dominant polycystic kidney disease, and cancer. Mutations in this gene affect susceptibility to cerebral malaria, septic shock, and Alzheimer disease. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

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