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Rabbit anti- Human IL-7 mAb (RMK0417)

This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

No significant cross-reactivity or interference was observed.

Placed at 37°C for 7 days, the stability of the standard curve all conform to CV <10%.

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货号: RMK0417
促销价:   ¥2100
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详细信息

产品名称
Rabbit anti- Human IL-7 mAb
货号
RMK0417
免疫原
Recombinant Human IL-7
纯化方式
Affinity purification
同种型
Rabbit IgG
存储溶液
Supplied as a 0.2um filtered solution in PBS with 0.1%Braveds MB-1,PH 7.8.
CrossReactivity
/
存储条件
Store at -20℃. Avoid freeze / thaw cycles. Preservative:0.05%ProClin 300.Avoid repeated freeze-thaw cycles.

* This package insert must be read in its entirety before using this product.

应用

Human IL-7 ELISA assay

  Recommended
Concentration
Sample
ELISA assayCapture2-8ug/mLRabbit anti-Human IL-7 mAb(Cat. No. RMK0417)
Detection0.05-0.2ug/mLRabbit anti-Human IL-7 mAb (Cat. No. RMK0418)
Standard15.63-1000pg/mLRecombinant IL-7 Protein

背景信息

The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. IL7 is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. IL7 plays an essential role in lymphoid cell survival, and in the maintenance of naive and memory T cells. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection can be a potent inducer of proinflammatory cytokines and chemokines which may defend against the infection, but may also mediate destructive lung injury. Elevated serum IL7 levels, together with several other circulating cytokines and chemokines, has been found to be associated with the severity of Coronavirus Disease 19 (COVID-19).

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