产品和服务 / 产品类型 / ELISA试剂盒 / ELISA 抗体对
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Human/Mouse/Rat/Monkey/Porcine/Bovine TGF beta 1 Sandwich Immunoassay
Recommended Concentration | Sample | ||
---|---|---|---|
ELISA | Capture | 2-8 μg/mL | Rabbit anti-Human/Mouse/Rat/Monkey/Porcine/Bovine TGF beta 1 mAb (Cat. No. RMK0521) |
Detection | 0.004-0.017 μg/mL | Rabbit anti-Human/Mouse/Rat/Monkey/Porcine/Bovine TGF beta 1 mAb (Cat. No. RMK0522) | |
Standard | 7.81-500 pg/mL | Recombinant Mouse/Rat Mature TGF-beta 1 Protein (Cat. No. RP00671) | |
Multiplex | Capture | 1.2-4.8 μg/mL | Rabbit anti-Human/Mouse/Rat/Monkey/Porcine/Bovine TGF beta 1 mAb (Cat. No. RMK0521) |
Detection | 0.125-0.5 μg/mL | Rabbit anti-Human/Mouse/Rat/Monkey/Porcine/Bovine TGF beta 1 mAb (Cat. No. RMK0522) | |
Standard | 6.86-5000 pg/mL | Recombinant Human Mature TGF-beta 1 Protein (Cat. No. RP01458) |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.