产品和服务 / 产品类型 / ELISA试剂盒 / ELISA 抗体对
This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.
* This package insert must be read in its entirety before using this product.
Mouse TGF beta 1 Sandwich Immunoassay
| Recommended Concentration | Sample | ||
|---|---|---|---|
| Multiplex | Capture | 1.2-4.8ug/mL | Rabbit anti-Mouse TGF beta 1 mAb (Cat. No. RMK0523) |
| Detection | 0.125-0.5ug/mL | Rabbit anti-Mouse TGF beta 1 mAb (Cat. No. RMK0524) | |
| Standard | 6.86-5000pg/mL | Recombinant Mouse/Rat Mature TGF-beta 1 Protein (Cat. No. RP00671) |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. Mice lacking a functional copy of this gene develop severe multifocal inflammatory disease, yolk sac defects and colon cancer.
