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Biotinylated Rabbit anti-Human IL-13 mAb (RMK0567B)

货号: RMK0567B
促销价:   ¥29525
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详细信息

产品名称
Biotinylated Rabbit anti-Human IL-13 mAb
货号
RMK0567B
免疫原
Recombinant Human IL-13 protein
纯化方式
Affinity purification
同种型
Rabbit IgG
内毒素水平
/
存储溶液
Supplied as a 0.2 μm filtered solution in PBS with 0.05% Proclin 300, pH 7.4.
CrossReactivity
/
存储条件
Store at -20℃.Avoid repeated freeze-thaw cycles.

* This package insert must be read in its entirety before using this product.

应用

Human IL-13 Sandwich Immunoassay

  Recommended
Concentration
Sample
ELISACapture0.5-2 μg/mLRabbit anti-Human IL-13 mAb (Cat. No. RMK0566)
Detection0.006-0.025 μg/mLRabbit anti-Human IL-13 mAb (Cat. No. RMK0567)
Standard46.88-3000 pg/mLRecombinant Human IL-13 Protein (Cat. No. RP01320)

背景信息

This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.