Targeting the miR-122/PKM2 autophagy axis relieves arsenic stress.
Journal
Journal of hazardous materials
ATAD3B is a mitophagy receptor mediating clearance of oxidative stress-induced damaged mitochondrial DNA
Autophagy-mediated compartmental cytoplasmic deletion is essential for tobacco pollen germination and male fertility
Foot-and-mouth disease virus VP1 degrades YTHDF2 through autophagy to regulate IRF3 activity for viral replication
Species
Homo sapiens,Sus scrofa
Environmentally relevant concentration of sulfamethoxazole-induced oxidative stress-cascaded damages in the intestine of grass carp and the therapeutic application of exogenous lycopene
Journal
Environmental pollution (Barking, Essex : 1987)
Species
Ctenopharyngodon idellus
Repression of the AURKA-CXCL5 axis induces autophagic cell death and promotes radiosensitivity in non-small-cell lung cancer
The lncRNA HULC functions as an oncogene by targeting ATG7 and ITGB1 in epithelial ovarian carcinoma
Journal
CELL DEATH & DISEASE
Battery wastewater induces nephrotoxicity via disordering the mitochondrial dynamics
Autophagy Enhancing Contributes to the Organ Protective Effect of Alpha-Lipoic Acid in Septic Rats.
Journal
Frontiers in Immunology
A high-concentrate diet induces inflammatory injury via regulating Ca2+/CaMKK-mediated autophagy in mammary gland tissue of dairy cows - PMC
Journal
Frontiers in immunology
Mercuric chloride induces sequential activation of ferroptosis and necroptosis in chicken embryo kidney cells by triggering ferritinophagy
Journal
Free radical biology & medicine
Calenduloside E protects against myocardial ischemia-reperfusion injury induced calcium overload by enhancing autophagy and inhibiting L-type Ca2+ channels …
Journal
Biomed Pharmacother
Knockdown of HSP110 attenuates hypoxia-induced pulmonary hypertension in mice through suppression of YAP/TAZ-TEAD4 pathway - PMC
Journal
Respiratory research
Hernandezine induces autophagic cell death in human pancreatic cancer cells via activation of the ROS/AMPK signaling pathway
Journal
Acta pharmacologica Sinica
Long-term exposure to copper induces autophagy and apoptosis through oxidative stress in rat kidneys
Journal
Ecotoxicology and Environmental Safety
Destruction of redox and mitochondrial dynamics co-contributes to programmed cell death in chicken kidney under arsenite or/and copper (II) exposure.
Journal
Ecotoxicology and environmental safety
Regulation of autophagy factors by oxidative stress and cardiac enzymes imbalance during arsenic or/and copper induced cardiotoxicity in Gallus gallus.
Journal
Ecotoxicology and Environmental Safety
Protective effects of curcumin on ATO-induced nephrotoxicity in ducks in relation to suppressed autophagy, apoptosis and dyslipidemia by regulating oxidative stress
Journal
Ecotoxicology and environmental safety
Cytoplasmic cargo receptor p62 inhibits avibirnavirus replication by mediating autophagic degradation of viral protein VP2
Defective Mitochondrial Dynamics and Protein Degradation Pathways Underlie Cadmium-Induced Neurotoxicity and Cell Death in Huntingtons Disease Striatal Cells - PMC
Journal
International journal of molecular sciences
Deficient tRNA posttranscription modification dysregulated the mitochondrial quality controls and apoptosis - PMC
Eicosapentaenoic Acid-Induced Autophagy Attenuates Intervertebral Disc Degeneration by Suppressing Endoplasmic Reticulum Stress, Extracellular Matrix Degradation, and Apoptosis
Journal
Front Cell Dev Biol
Autophagy Is a Defense Mechanism Inhibiting Invasion and Inflammation During High-Virulent Haemophilus parasuis Infection in PK-15 Cells.
Journal
Frontiers in Cellular and Infection Microbiology
Ag120-Mediated Inhibition of ASCT2-Dependent Glutamine Transport has an Anti-Tumor Effect on Colorectal Cancer Cells
Journal
Frontiers in pharmacology
Enhancing the retrograde axonal transport by curcumin promotes autophagic flux in N2a/APP695swe cells.
5-Heptadecylresorcinol Ameliorates Obesity-Associated Skeletal Muscle Mitochondrial Dysfunction through SIRT3-Mediated Mitophagy
Journal
Journal of agricultural and food chemistry
Polystyrene microplastics mediate inflammatory responses in the chicken thymus by Nrf2/NF-κB pathway and trigger autophagy and apoptosis
Journal
Environmental toxicology and pharmacology
Platelet-rich plasma-derived exosomes attenuate intervertebral disc degeneration by promoting NLRP3 autophagic degradation in macrophages
Journal
International immunopharmacology
Berberine mitigates IL-21/IL-21R mediated autophagic influx in fibroblast-like synoviocytes and regulates Th17/Treg imbalance in rheumatoid arthritis.
Journal
Apoptosis : an international journal on programmed cell death
Curcumin antagonizes inflammation and autophagy induced by arsenic trioxide through immune protection in duck spleen
Journal
Environmental science and pollution research international
Evaluation of toxic effects induced by arsenic trioxide or/and antimony on autophagy and apoptosis in testis of adult mice
Journal
Environmental science and pollution research international
The role of mitochondrial dynamics imbalance in hexavalent chromium-induced apoptosis and autophagy in rat testis
Journal
Chemico-biological interactions
BMP4 participates in the pathogenesis of PCOS by regulating glucose metabolism and autophagy in granulosa cells under hyperandrogenic environment
Journal
The Journal of steroid biochemistry and molecular biology
Autophagy induces apoptosis and death of T lymphocytes in the spleen of pigs infected with CSFV
Journal
Scientific reports
Suppression of autophagy through JAK2/STAT3 contributes to the therapeutic action of rhynchophylline on asthma
Journal
BMC Complement Med Ther
Resveratrol ameliorates lipopolysaccharide-induced anxiety-like behavior by attenuating YAP-mediated neuro-inflammation and promoting hippocampal autophagy in mice
Journal
Toxicology and applied pharmacology
Arsenic (III) and/or copper (II) induces oxidative stress in chicken brain and subsequent effects on mitochondrial homeostasis and autophagy
Synergistic effect of copper and arsenic upon oxidative stress, inflammation and autophagy alterations in brain tissues of Gallus gallus
Journal
Journal of Inorganic Biochemistry
The Synergistic Effect of TRPV1 on Oxidative Stress-Induced Autophagy and Apoptosis in Microglia
Journal
Anal Cell Pathol (Amst)
Copper-Mediated Mitochondrial Fission/Fusion Is Associated with Intrinsic Apoptosis and Autophagy in the Testis Tissues of Chicken.
Journal
Biological Trace Element Research
The apoptosis in arsenic-induced oxidative stress is associated with autophagy in the testis tissues of chicken
Folate inhibits lipid deposition via the autophagy pathway in chicken hepatocytes - PMC
Myocardial infarction-induced anxiety-like behavior is associated with epigenetic alterations in the hippocampus of rat
Characterization, functional and signaling elucidation of pigeon (Columba livia) interferon-α: Knockdown p53 negatively modulates antiviral response
Journal
Developmental and Comparative Immunology
Sodium butyrate induces autophagic apoptosis of nasopharyngeal carcinoma cells by inhibiting AKT/mTOR signaling.
Journal
Biochemical and biophysical research communications
Angiotensin-(1-7) suppresses airway inflammation and airway remodeling via inhibiting ATG5 in allergic asthma - PMC
Journal
BMC pulmonary medicine
Ischemia reperfusion myocardium injuries in type 2 diabetic rats: Effects of ketamine and insulin on LC3-II and mTOR expression - PMC
Journal
International journal of immunopathology and pharmacology
Autophagy is a defense mechanism controlling Streptococcus suis serotype 2 infection in murine microglia cells
GPNMB mitigates Alzheimer's disease and enhances autophagy via suppressing the mTOR signal
Melatonin mitigates Chloroquine-induced defects in porcine immature Sertoli cells
Branched-chain amino acid transaminase 1 inhibition attenuates childhood asthma in mice by effecting airway remodeling and autophagy
Journal
Respiratory physiology & neurobiology
Application
WB, IHC, ELISA
GL-V9 reverses adriamycin resistance in hepatocellular carcinoma cells by affecting JNK2-related autophagy
Journal
2020 Jul Chin J Nat Med
Effects of Prunus Tomentosa Thumb Total Flavones on adjuvant arthritis in rats and regulation of autophagy - PMC
Journal
Technology and health care : official journal of the European Society for Engineering and Medicine
Interleukin-22 alleviates arginine-induced pancreatic acinar cell injury via the regulation of intracellular vesicle transport system: Evidence from proteomic analysis - PMC
Journal
EXPERIMENTAL AND THERAPEUTIC MEDICINE
The Hyperproliferation Mechanism of Cholesteatoma Based on Proteomics: SNCA Promotes Autophagy-Mediated Cell Proliferation through the PI3K/AKT
Journal
Molecular & cellular proteomics : MCP
PVT1 alleviates hypoxia-induced endothelial apoptosis by enhancing autophagy via the miR-15b-5p/ATG14 and miR-424-5p/ATG14 axis
p62/SQSTM1 protects against cisplatin-induced oxidative stress in kidneys by mediating the cross talk between autophagy and the Keap1-Nrf2 signalling pathway
Journal
Free radical research