UBE2M-mediated neddylation of TRIM21 regulates obesity-induced inflammation and metabolic disorders
NLRP12 collaborates with NLRP3 and NLRC4 to promote pyroptosis inducing ganglion cell death of acute glaucoma
Journal
Molecular Neurodegeneration
SARS-CoV-2 triggers inflammatory responses and cell death through caspase-8 activation
Journal
Signal Transduct Target Ther
Intravenous
Transplantation of an Ischemic-specific
Peptide-TPP-mitochondrial Compound Alleviates Myocardial Ischemic
Reperfusion Injury - PMC
Gut-derived memory T17 cells exacerbate sepsis-induced acute lung injury in mice - PMC
Journal
Nature communications
Inhibition of GSDMD-dependent pyroptosis decreased methamphetamine self-administration in rats
Journal
Brain, behavior, and immunity
Cadmium exposure triggers Oxidative stress, Necroptosis, Th1/Th2 imbalance and promotes Inflammation through the TNF-α/NF-κB pathway in swine small intestine
Daucosterol confers protection against T-2 toxin induced blood-brain barrier toxicity through the PGC-1-mediated defensive response in vitro and in vivo
Journal
Journal of hazardous materials
Oral delivery of anti-TNF antibody shielded by natural polyphenol-mediated supramolecular assembly for inflammatory bowel disease therapy
Injectable extracellular vesicle-released self-assembling peptide nanofiber hydrogel as an enhanced cell-free therapy for tissue regeneration
Journal
Journal of Controlled Release : Official Journal of the Controlled Release Society
Reactive oxygen species trigger NF-B-mediated NLRP3 inflammasome activation involvement in low-dose CdTe QDs exposure-induced hepatotoxicity
Cadmium exposure induces pyroptosis in testicular tissue by increasing oxidative stress and activating the AIM2 inflammasome pathway
Journal
The Science of the total environment
A self-assembling peptide hydrogel-based drug co-delivery platform to improve tissue repair after ischemia-reperfusion injury
Journal
Acta Biomaterialia
LncRNA Neat1 promotes the macrophage inflammatory response and acts as a therapeutic target in titanium particle-induced osteolysis
Journal
Acta biomaterialia
Medioresinol as a novel PGC-1 activator prevents pyroptosis of endothelial cells in ischemic stroke through PPAR-GOT1 axis
Sulforaphane attenuates microglia-mediated neuronal necroptosis through down-regulation of MAPK/NF-B signaling pathways in LPS-activated BV-2 microglia
Journal
Pharmacological Research
Phloretin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice by regulating the gut microbiota
Journal
Pharmacological research
SFTSV Infection Induces BAK/BAX-Dependent Mitochondrial DNA Release to Trigger NLRP3 Inflammasome Activation
Species
Homo sapiens, Mus musculus
PARP16-Mediated Stabilization of Amyloid Precursor Protein mRNA Exacerbates Alzheimers Disease Pathogenesis - PMC
Endothelial cell pyroptosis plays an important role in Kawasaki disease via HMGB1/RAGE/cathespin B signaling pathway and NLRP3 inflammasome activation
Journal
Cell death & disease
Nicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosis
Journal
Cell Death and Disease
Dehydroepiandrosterone exacerbates nigericin-induced abnormal autophagy and pyroptosis via GPER activation in LPS-primed macrophages
Journal
Cell death & disease
Substantia nigra Smad3 signaling deficiency: relevance to aging and Parkinson’s disease and roles of microglia, proinflammatory factors, and MAPK
Journal
Journal of Neuroinflammation
Elamipretide alleviates pyroptosis in traumatically injured spinal cord by inhibiting cPLA2-induced lysosomal membrane permeabilization - PMC
Journal
Journal of neuroinflammation
Positive interaction between GPER and β-alanine in the dorsal root ganglion uncovers potential mechanisms: mediating continuous neuronal sensitization and neuroinflammation responses in neuropathic pain - PMC
Journal
Journal of neuroinflammation
Host Gasdermin D restrains systemic endotoxemia by capturing Proteobacteria in the colon of high-fat diet-feeding mice
Melanin-like polydopamine nanoparticles mediating anti-inflammatory and rescuing synaptic loss for inflammatory depression therapy - PMC
Journal
Journal of nanobiotechnology
Gut microbiota-mediated metabolic restructuring aggravates emotional deficits after anesthesia/surgery in rats with preoperative stress - PMC
Journal
Frontiers in immunology
Exercise training-attenuated insulin resistance and liver injury in elderly pre-diabetic patients correlates with NLRP3 inflammasome - PMC
Journal
Frontiers in immunology
Indoleamine 2,3-dioxygenase mediates the therapeutic effects of adipose-derived stromal/stem cells in experimental periodontitis by modulating macrophages through the kynurenine-AhR-NRF2 pathway - PMC
Journal
Molecular metabolism
miR-29b-3p regulates cardiomyocytes pyroptosis in CVB3-induced myocarditis through targeting DNMT3A - PMC
Journal
Cellular & molecular biology letters
Elevated branched-chain α-keto acids exacerbate macrophage oxidative stress and chronic inflammatory damage in type 2 diabetes mellitus
Journal
Free Radic Biol Med
Inorganic nitrate alleviates irradiation-induced salivary gland damage by inhibiting pyroptosis
Journal
Free Radic Biol Med
Low shear stress induced vascular endothelial cell pyroptosis by TET2/SDHB/ROS pathway
Journal
Free Radical Biology And Medicine
MCC950 attenuates doxorubicin-induced myocardial injury in vivo and in vitro by inhibiting NLRP3-mediated pyroptosis
Journal
Biomed Pharmacother
DHA attenuates Aβ-induced necroptosis through the RIPK1/RIPK3 signaling pathway in THP-1 monocytes
Journal
Biomedicine & Pharmacotherapy
LongShengZhi capsule inhibits doxorubicin-induced heart failure by anti-oxidative stress
Journal
Biomedicine & Pharmacotherapy
Melatonin alleviates doxorubicin-induced cardiotoxicity via inhibiting oxidative stress, pyroptosis and apoptosis by activating Sirt1/Nrf2 pathway
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Negative regulation of Nod-like receptor protein 3 inflammasome activation by T cell Ig mucin-3 protects against peritonitis
Journal
Journal of Immunology
Ginsenoside Rg1 exerts neuroprotective effects in 3-nitropronpionic acid-induced mouse model of Huntington’s disease via suppressing MAPKs and NF-κB pathways in the striatum
Journal
Acta Pharmacologica Sinica
NOX2 activation contributes to cobalt nanoparticles-induced inflammatory responses and Tau phosphorylation in mice and microglia
Journal
Ecotoxicol Environ Saf
Inflammasome/NF-κB translocation inhibition via PPARγ agonist mitigates inorganic mercury induced nephrotoxicity
Journal
Ecotoxicol Environ Saf
Cadmium exposure induces pyroptosis of TM4 cells through oxidative stress damage and inflammasome activation
Journal
Ecotoxicology and environmental safety
3, 4-benzopyrene aggravates myocardial ischemiareperfusion injury-induced pyroptosis through inhibition of autophagy-dependent NLRP3 degradation
Journal
Ecotoxicology and environmental safety
Species
Mus musculus, Rattus norvegicus
TAB1 regulates glycolysis and activation of macrophages in diabetic nephropathy
Polyacetylene glycoside attenuates ischemic kidney injury by co-inhibiting inflammation, mitochondria dysfunction and lipotoxicity
Anti-inflammatory activity of carvacrol protects the heart from lipopolysaccharide-induced cardiac dysfunction by inhibiting pyroptosis via NLRP3/Caspase1/Gasdermin …
(R)-Ketamine ameliorates lethal inflammatory responses and multi-organ injury in mice induced by cecum ligation and puncture
GYY4137 alleviates sepsis-induced acute lung injury in mice by inhibiting the PDGFRβ/Akt/NF-κB/NLRP3 pathway
Punicalagin Protects Diabetic Nephropathy by Inhibiting Pyroptosis Based on TXNIP/NLRP3 Pathway
Anticancer activity of Bacopa monnieri through apoptosis induction and mitophagy-dependent NLRP3 inflammasome inhibition in oral squamous cell carcinoma
Journal
Phytomedicine : international journal of phytotherapy and phytopharmacology
Shexiang Baoxin Pill attenuates myocardial ischemia/reperfusion injury by activating autophagy via modulating the ceRNA-Map3k8 pathway
Journal
Phytomedicine : international journal of phytotherapy and phytopharmacology
Ginsenoside Rb1 ameliorates cardiotoxicity triggered by aconitine via inhibiting calcium overload and pyroptosis
Journal
Phytomedicine : international journal of phytotherapy and phytopharmacology
CDC20 inhibition alleviates fibrotic response of renal tubular epithelial cells and fibroblasts by regulating nuclear translocation of -catenin
Journal
Biochimica et biophysica acta. Molecular basis of disease
Maternal High-Fat Diet Leads to Non-alcoholic Fatty Liver Disease Through Upregulating Hepatic SCD1 Expression in Neonate Rats
GDF-11 Protects the Traumatically Injured Spinal Cord by Suppressing Pyroptosis and Necroptosis via TFE3-Mediated Autophagy Augmentation
Journal
Oxid Med Cell Longev
SIRT7 Regulates Lipopolysaccharide-Induced Inflammatory Injury by Suppressing the NF-κB Signaling Pathway.
Journal
Oxidative medicine and cellular longevity
Simvastatin Inhibits NLRP3 Inflammasome Activation and Ameliorates Lung Injury in Hyperoxia-Induced Bronchopulmonary Dysplasia via the KLF2-Mediated Mechanism
Journal
Oxidative medicine and cellular longevity
Liraglutide, a TFEB-Mediated Autophagy Agonist, Promotes the Viability of Random-Pattern Skin Flaps
Journal
Oxid Med Cell Longev
Oxymatrine loaded nitric oxide-releasing liposomes for the treatment of ulcerative colitis
Sustained release of hepatocyte growth factor by cationic self-assembling peptide/heparin hybrid hydrogel improves β-cell survival and function through modulating inflammatory response.
Journal
International journal of nanomedicine
Total saponins of panax ginseng via the CX3CL1/CX3CR1 axis attenuates neuroinflammation and exerted antidepressant‐like effects in chronic unpredictable mild …
Journal
Phytotherapy research : PTR
Replacing dietary sodium selenite with biogenic selenium nanoparticles improves the growth performance and gut health of early-weaned piglets
Toll-like receptor 4 mediates methamphetamine-induced neuroinflammation through Caspase-11 signaling pathway in astrocytes
Journal
Frontiers in Molecular Neuroscience
Inflammasome Inhibition Prevents Motor Deficit and Cerebellar Degeneration Induced by Chronic Methamphetamine Administration
Journal
Frontiers in molecular neuroscience
Ferulic Acid Improves Depressive-Like Behavior in Prenatally-Stressed Offspring Rats via Anti-Inflammatory Activity and HPA Axis.
Journal
International journal of molecular sciences
E3 Ubiquitin Ligase FBXO3 Drives Neuroinflammation to Aggravate Cerebral Ischemia/Reperfusion Injury - PMC
Journal
International journal of molecular sciences
Mallotucin D, a Clerodane Diterpenoid from Croton crassifolius, Suppresses HepG2 Cell Growth via Inducing Autophagic Cell Death and Pyroptosis - PMC
Journal
International journal of molecular sciences
-Caryophyllene Ameliorates MSU-Induced Gouty Arthritis and Inflammation Through Inhibiting NLRP3 and NF-B Signal Pathway: In Silico and In Vivo
Platelet-Derived Growth Factor-BB Inhibits Intervertebral Disc Degeneration via Suppressing Pyroptosis and Activating the MAPK Signaling Pathway
Journal
Frontiers in pharmacology
Evodiamine Attenuates Experimental Colitis Injury Via Activating Autophagy and Inhibiting NLRP3 Inflammasome Assembly
Journal
Frontiers in Pharmacology
Protein-protein interactions between RUNX3 and ZEB1 in chronic lung injury induced by methamphetamine abuse - PMC
Journal
Frontiers in pharmacology
Treadmill exercise can regulate the redox balance in the livers of APP/PS1 mice and reduce LPS accumulation in their brains through the gut-liver-kupffer cell axis - PMC
Androgen aggravates liver fibrosis by activation of NLRP3 inflammasome in CCl4 induced liver injury mouse model
Journal
American Journal of physiology. Endocrinology and Metabolism
N-Ethyl-2-Pyrrolidinone-Substituted Flavan-3-Ols with Anti-inflammatory Activity in Lipopolysaccharide-Stimulated Macrophages Are Storage-Related Marker Compounds for Green Tea
Sodium-Glucose Co-transporter-2 Inhibitor of Dapagliflozin Attenuates Myocardial Ischemia/Reperfusion Injury by Limiting NLRP3 Inflammasome Activation and Modulating Autophagy
Journal
Frontiers in cardiovascular medicine
Jmjd3 regulates inflammasome activation and aggravates DSS-induced colitis in mice
Journal
FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology
Intranasal administration of β‐1, 3‐galactosyltransferase 2 confers neuroprotection against ischemic stroke by likely inhibiting oxidative stress and NLRP3 …
Journal
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
CVB3 Inhibits NLRP3 Inflammasome Activation by Suppressing NF-κB Pathway and ROS Production in LPS-Induced Macrophages - PMC
Abnormal Insulin-like Growth Factor 1 Signaling Regulates Neuropathic Pain by Mediating the Mechanistic Target of Rapamycin-Related Autophagy and Neuroinflammation in Mice
MiR-144-5p limits experimental abdominal aortic aneurysm formation by mitigating M1 macrophage-associated inflammation: Suppression of TLR2 and OLR1
Journal
Journal of Molecular and Cellular Cardiology
Carnosine alleviates podocyte injury in diabetic nephropathy by targeting caspase-1-mediated pyroptosis
Journal
Int Immunopharmacol
BMP9 promotes methionine- and choline-deficient diet-induced nonalcoholic steatohepatitis in non-obese mice by enhancing NF-κB dependent macrophage polarization
Journal
Int Immunopharmacol
Inhibition of LOX-1 prevents inflammation and photoreceptor cell death in retinal degeneration
Journal
International Immunopharmacology
Rosuvastatin promotes survival of random skin flaps through AMPK-mTOR pathway-induced autophagy
Journal
International immunopharmacology
Microglial pyroptosis in hippocampus mediates sevolfurane-induced cognitive impairment in aged mice via ROS-NLRP3 inflammasome pathway
Journal
International immunopharmacology
Mesenchymal stem cells-derived extracellular vesicles-shuttled microRNA-223-3p suppress lipopolysaccharide-induced cardiac inflammation, pyroptosis, and
Journal
International immunopharmacology
Nuciferine alleviates intestinal inflammation by inhibiting MAPK/NF-κB and NLRP3/Caspase 1 pathways in vivo and in vitro
Journal
International immunopharmacology
The p75 neurotrophin receptor as a novel intermediate in L-dopa-induced dyskinesia in experimental Parkinson's disease
Acid-sensing ion channel 1a exacerbates renal ischemia-reperfusion injury through the NF-κB/NLRP3 inflammasome pathway - PMC
Journal
Journal of molecular medicine (Berlin, Germany)
A novel nano material for anti-cerebral ischemia: Preparation and Application of Borneol Angelica Polysaccharide Liposomes
Journal
Journal of liposome research
The Protective Effects of Ginseng Polysaccharides and Their Effective Subfraction against Dextran Sodium Sulfate-Induced Colitis
Journal
Foods (Basel, Switzerland)
Bioglass promotes wound healing by inhibiting endothelial cell pyroptosis through regulation of the connexin 43/reactive oxygen species (ROS) signaling pathway
Seneca Valley Virus 3C Protease Induces Pyroptosis by Directly Cleaving Porcine Gasdermin D
Journal
Journal of immunology (Baltimore, Md. : 1950)
Carthamin yellow improves cerebral ischemia-reperfusion injury by attenuating inflammation and ferroptosis in rats.
PD0325901, an ERK inhibitor, attenuates RANKL‐induced osteoclast formation and mitigates cartilage inflammation by inhibiting the NF-κB and MAPK …
Journal
Bioorganic chemistry
Complement C5 activation promotes type 2 diabetic kidney disease via activating STAT3 pathway and disrupting the gutkidney axis
Glycogen synthase kinase-3 inhibition decreases inflammation and relieves cancer induced bone pain via reducing Drp1-mediated mitochondrial damage - PMC
Journal
Journal of cellular and molecular medicine
The role of the gutmicrobiotabrain axis via the subdiaphragmatic vagus nerve in chronic inflammatory pain and comorbid spatial working memory impairment in
Journal
Journal of psychiatric research
Harmine mitigates LPS-induced acute kidney injury through inhibition of the TLR4-NF-B/NLRP3 inflammasome signalling pathway in mice.
Journal
European journal of pharmacology
Alternanthera brasiliana L. extract alleviates carbon tetrachloride-induced liver injury and fibrotic changes in mice: Role of matrix metalloproteinases and TGF-β/Smad …
Journal
Journal of ethnopharmacology
Tongxinluo attenuates atherosclerosis by inhibiting ROS/NLRP3/caspase-1-mediated endothelial cell pyroptosis
Journal
Journal of ethnopharmacology
Hyperoside attenuates pregnancy loss through activating autophagy and suppressing inflammation in a rat model
Commensal Escherichia coli Aggravates Acute Necrotizing Pancreatitis through Targeting of Intestinal Epithelial Cells.
Journal
Applied and Environmental Microbiology
Hesperetin ameliorates spinal cord injury in rats through suppressing apoptosis, oxidative stress and inflammatory response
Journal
European journal of pharmacology
Naringin Exhibited Therapeutic Effects against DSS-Induced Mice Ulcerative Colitis in Intestinal Barrier-Dependent Manner
Hyperkeratinization and Proinflammatory Cytokine Expression in Meibomian Glands Induced by Staphylococcus aureus
Journal
Invest Ophthalmol Vis Sci
Myrtenal and β-caryophyllene oxide screened from Liquidambaris Fructus suppress NLRP3 inflammasome components in rheumatoid arthritis
Journal
BMC Complement Med Ther
MLKL aggravates Ox-LDL-induced cell pyroptosis via activation of NLRP3 inflammasome in human umbilical vein endothelial cells
Integrin-α9 and its corresponding ligands play regulatory roles in chronic periodontitis
C/EBP Promotes LPS-Induced IL-1 Transcription and Secretion in Alveolar Macrophages via NOD2 Signaling - PMC
Journal
Journal of inflammation research
Shikonin attenuates rheumatoid arthritis by targeting SOCS1/JAK/STAT signaling pathway of fibroblast like synoviocytes
ROS-mediated NRF2/p-ERK1/2 signaling-involved mitophagy contributes to macrophages activation induced by CdTe quantum dots
Lipopolysaccharide-Induced Microglial Neuroinflammation: Attenuation by FK866
Species
Homo sapiens,Rattus norvegicus
TAK1 Reduces Surgery-induced Overactivation of RIPK1 to Relieve Neuroinflammation and Cognitive Dysfunction in Aged Rats
Journal
Neurochemical research
Melatonin protects human nucleus pulposus cells from pyroptosis by regulating Nrf2 via melatonin membrane receptors - PMC
Journal
Bone & joint research
Involvement of RhoA/ROCK Signaling in Aβ-Induced Chemotaxis, Cytotoxicity and Inflammatory Response of Microglial BV2 Cells.
Journal
Cellular and molecular neurobiology
18-Glycyrrhetinic Acid Alleviates P. multocida-Induced Vascular Endothelial Inflammation by PARP1-Mediated NF-B and HMGB1 Signalling Suppression in PIEC Cells - PMC
Journal
Infection and drug resistance
VX-765 attenuates atherosclerosis in ApoE deficient mice by modulating VSMCs pyroptosis
Journal
Experimental Cell Research
Species
Homo sapiens, Mus musculus
Puerarin decreases bone loss and collagen destruction in rats with ligature-induced periodontitis
Journal
Journal Of Periodontal Research
Downregulation of IL-1/p38 mitogen activated protein kinase pathway by diacerein protects against kidney ischemia/reperfusion injury in rats
Kaempferol alleviates corneal transplantation rejection by inhibiting NLRP3 inflammasome activation and macrophage M1 polarization via promoting autophagy
2-Bromopalmitate decreases spinal inflammation and attenuates oxaliplatin-induced neuropathic pain via reducing Drp1-mediated mitochondrial dysfunction - PMC
Treadmill exercise mitigates neuroinflammation and increases BDNF via activation of SIRT1 signaling in a mouse model of T2DM
Network pharmacology and experimental verification to decode the action of Qing Fei Hua Xian Decotion against pulmonary fibrosis - PMC
Inhibition of miR-423-5p exerts neuroprotective effects in an experimental rat model of cerebral ischemia/reperfusion injury
High-dose remifentanil exacerbates myocardial ischemia-reperfusion injury through activation of calcium-sensing receptor-mediated pyroptosis - PMC
Journal
International journal of medical sciences
Emodin suppresses oxaliplatininduced neuropathic pain by inhibiting COX2/NFB mediated spinal inflammation
Journal
Journal of biochemical and molecular toxicology
Flavonoid-enriched extract from Millettia speciosa Champ prevents obesity by regulating thermogenesis and lipid metabolism in high-fat diet-induced obese C57BL/6 mice
Journal
Food science & nutrition
Lipopolysaccharide Promotes Inflammatory Response via Enhancing IFIT1 Expression in Human Umbilical Vein Endothelial Cells
2-Bromopalmitate attenuates inflammatory pain by maintaining mitochondrial fission/fusion balance and function
Journal
Acta biochimica et biophysica Sinica
Histidine ameliorates elastase-and lipopolysaccharide-induced lung inflammation by inhibiting the activation of the NLRP3 inflammasome
Journal
Acta Biochim Biophys Sin (Shanghai)
AMPK activation attenuates cancer-induced bone pain by reducing mitochondrial dysfunction-mediated neuroinflammation - PMC
Journal
Acta biochimica et biophysica Sinica
Macrophage-derived exosomal miRNA-141 triggers endothelial cell pyroptosis by targeting NLRP3 to accelerate sepsis progression - PMC
Journal
International journal of immunopathology and pharmacology
lncRNA GAS5 promotes pyroptosis in COPD by functioning as a ceRNA to regulate the miR‑223‑3p/NLRP3 axis
Journal
Molecular medicine reports
Klotho alleviates NLRP3 inflammasome-mediated neuroinflammation in a temporal lobe epilepsy rat model by activating the Nrf2 signaling pathway
Journal
Epilepsy & behavior : E&B
Species
Oryctolagus cuniculus
Minocycline alleviates NLRP3 inflammasome-dependent pyroptosis in monosodium glutamate-induced depressive rats
Journal
Biochemical and Biophysical Research Communications
Food with calorie restriction reduces the development of atherosclerosis in apoE-deficient mice
Journal
Biochemical and Biophysical Research Communications
Macrophage pyroptosis is mediated by immunoproteasome subunit β5i (LMP7) in abdominal aortic aneurysm
Journal
Biochem Biophys Res Commun
Hypoxic preconditioned aged BMSCs accelerates MI injury repair by modulating inflammation, oxidative stress and apoptosis
Journal
Biochemical and biophysical research communications
MiR-124–3p promotes trophoblast cell HTR-8/SVneo pyroptosis by targeting placental growth factor
Toxoplasma gondii rhoptry protein (TgROP18) enhances the expression of pro-inflammatory factor in LPS/IFN--induced murine BV2 microglia cells via NF-B signal
Bisdemethoxycurcumin, a curcumin, protects chondrocytes, and reduces cartilage inflammation via the NRF2/HO-1/NLRP3 pathway - PMC
Journal
Immunity, inflammation and disease
Long non-coding RNA RP11-490M8.1 inhibits lipopolysaccharide-induced pyroptosis of human umbilical vein endothelial cells via the TLR4/NF-κB pathway
Increasing hypothalamic nucleobindin 2 levels and decreasing hypothalamic inflammation in obese male mice via diet and exercise alleviate obesity-associated hypogonadism.
Suppressed Immune-Related Profile Rescues Abortion-Prone Fetuses: A Novel Insight Into the CBA/J× DBA/2J Mouse Model
Journal
Reproductive sciences (Thousand Oaks, Calif.)
Bone marrow-derived mesenchymal stem cell-conditioned medium ameliorates diabetic foot ulcers in rats - PMC
Journal
Clinics (Sao Paulo, Brazil)
Shen Shuai II Recipe Attenuates Renal Interstitial Fibrosis by Improving Hypoxia via the IL-1β/c-Myc Pathway
Journal
Evid Based Complement Alternat Med
Downregulation of ROCK2 attenuates alcohol-induced inflammation and oxidative stress in astrocytes
Hepatitis B virus X mediates podocyte pyroptosis by regulating the ROS/NLRP3 signaling pathway in hepatitis B virus-associated glomerulonephritis
Journal
Iranian journal of basic medical sciences
Ononin alleviates DSS-induced colitis through inhibiting NLRP3 inflammasome via triggering mitophagy - PMC
Journal
Immunity, inflammation and disease
Overexpression of miR-224-5p alleviates allergic rhinitis in mice via the TLR4/MyD88/NF-κB pathway
Schisandrin ameliorates cognitive deficits, endoplasmic reticulum stress and neuroinflammation in STZ-induced Alzheimer's disease rats
Journal
Experimental Animals
MicroRNA-135b alleviates MPP+-mediated Parkinson's disease in in vitro model through suppressing FoxO1-induced NLRP3 inflammasome and pyroptosis.
Journal
Journal of clinical neuroscience
Notoginsenoside R1 alleviates spinal cord injury by inhibiting oxidative stress, neuronal apoptosis, and inflammation via activating the nuclear factor erythroid 2 related factor 2/heme oxygenase-1 signaling pathway - PMC
N-acetylserotonin alleviates retinal ischemia-reperfusion injury via HMGB1/RAGE/NF-B pathway in rats - PMC
Journal
International journal of ophthalmology
Histone Deacetylase9 Represents the Epigenetic Promotion of M1 Macrophage Polarization and Inflammatory Response via TLR4 Regulation - PMC
Journal
BioMed research international
Cyclic helix B peptide alleviates proinflammatory cell death and improves functional recovery after traumatic spinal cord injury
Differential inflammatory responses of the native left and right ventricle associated with donor heart preservation