Recombinant protein (or fragment).This information is considered to be commercially sensitive.
克隆号
ARC57886
产品形式
Liquid
偶联物
ABflo® 647. Ex:648nm. Em:664nm.
克隆号
ARC57886
产品形式
Liquid
偶联物
ABflo® 647. Ex:648nm. Em:664nm.
细胞定位
Nucleus.
存储缓冲液
Store at 2-8℃. Avoid freeze. Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal POZ domain. This protein acts as a sequence-specific repressor of transcription, and has been shown to modulate the transcription of STAT-dependent IL-4 responses of B cells. This protein can interact with a variety of POZ-containing proteins that function as transcription corepressors. This gene is found to be frequently translocated and hypermutated in diffuse large-cell lymphoma (DLCL), and may be involved in the pathogenesis of DLCL. Alternatively spliced transcript variants encoding different protein isoforms have been found for this gene.
