Flow Cytometry analysis of MC38 tumor microenvironment, using ABflo® 647 Rabbit anti-Mouse CD8a mAb (A23904), PE Rabbit anti-Mouse CD4 mAb (A25933), ABflo® 450 Rabbit anti-Mouse CD45 mAb (A27197) and ABflo® 488 Rabbit anti-Mouse CD11b mAb (A24094), clearly classified positive and negative cells.
Flow cytometry analysis of mouse brain tissue using ABflo® 488 Rabbit anti-Mouse CD11b mAb (A24094) and ABflo® 594 Rabbit anti-Mouse CD45 mAb (A23709) at 1:200 dilution. clearly classified positive and negative cells.
Enables complement component C3b binding activity; heparan sulfate proteoglycan binding activity; and heparin binding activity. Contributes to cargo receptor activity. Involved in several processes, including central nervous system development; endocytosis; and positive regulation of neuron death. Acts upstream of or within several processes, including activated T cell proliferation; leukocyte migration; and microglia development. Located in external side of plasma membrane and nucleus. Is integral component of membrane. Part of integrin alphaM-beta2 complex. Is expressed in several structures, including central nervous system; heart; lymphatic vessel; thymus; and yolk sac. Human ortholog(s) of this gene implicated in lupus nephritis. Orthologous to human ITGAM (integrin subunit alpha M).
