Recombinant protein (or fragment).This information is considered to be commercially sensitive.
克隆号
ARC64145
产品形式
Liquid
偶联物
PE. Ex:565nm. Em:574nm.
克隆号
ARC64145
产品形式
Liquid
偶联物
PE. Ex:565nm. Em:574nm.
细胞定位
Membrane, external side of plasma membrane, plasma membrane, Single-pass type I membrane protein.
存储缓冲液
Store at 2-8℃. Avoid freeze. Buffer: PBS containing 0.2% BSA, preserved with proclin300 or sodium azide (as specified on the Certificate of Analysis), pH 7.3.
Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity.
