ERCC6L2 promotes DNA orientation-specific recombination in mammalian cells
Circular RNA hsa_circ_0000467 promotes colorectal cancer progression by promoting eIF4A3-mediated c-Myc translation - PMC
CD146 bound to LCK promotes T cell receptor signaling and antitumor immune responses in mice
Journal
The Journal of clinical investigation
Controlled-release hydrogel loaded with magnesium-based nanoflowers synergize immunomodulation and cartilage regeneration in tendon-bone healing - PMC
Journal
Bioactive materials
REV7 is required for processing AID initiated DNA lesions in activated B cells
Unveiling E2F4, TEAD1 and AP-1 as regulatory transcription factors of the replicative senescence program by multi-omics analysis
Compound Danshen Dripping Pill inhibits hypercholesterolemia/atherosclerosis-induced heart failure in ApoE and LDLR dual deficient mice via multiple mechanisms
Journal
Acta Pharmaceutica Sinica B
Genetic variation in ZmKW1 contributes to kernel weight and size in dent corn and popcorn
Journal
Plant biotechnology journal
Circulating miR-338 Cluster activities on osteoblast differentiation: Potential Diagnostic and Therapeutic Targets for Postmenopausal Osteoporosis.
Effective Sonosensitizer Delivery by Redox Sensitive Nanoparticles for Prostate Cancer Sonodynamic Therapy via Amplifying Oxidative Stress and Peroxidation
Journal
Advanced healthcare materials
Elevated Placental microRNA-155 Is a Biomarker of a Preeclamptic Subtype
Journal
Hypertension (Dallas, Tex. : 1979)
Cellular and Molecular
Insights into the Divergence
of Neural Stem Cells on Matrigel and Poly-l-lysine
Interfaces - PMC
Journal
ACS applied materials & interfaces
Cell membrane-coated human hair nanoparticles for precise disease therapies - PMC
Journal
Journal of nanobiotechnology
Sertoli cell survival and barrier function are regulated by miR-181c/d-Pafah1b1 axis during mammalian spermatogenesis - PMC
Journal
Cellular and molecular life sciences : CMLS
Species
Mus musculus、Sus scrofa
Rapamycin targets STAT3 and impacts c-Myc to suppress tumor growth
Mast cells inhibit colorectal cancer development by inducing ER stress through secreting Cystatin C
PFKFB4 facilitates palbociclib resistance in oestrogen receptor‐positive breast cancer by enhancing stemness
Journal
Cell proliferation
CD36 as a Molecular Target of Functional DNA Aptamer NAFLD01 Selected against NAFLD Cells
tRF-33-P4R8YP9LON4VDP inhibits gastric cancer progression via modulating STAT3 signaling pathway in an AGO2-dependent manner
Exosomes Derived from Human Palatal Mesenchymal Cells Mediate Intercellular Communication During Palatal Fusion by Promoting Oral Epithelial Cell Migration
Journal
International journal of nanomedicine
Natural Astaxanthin Improves Testosterone Synthesis and Sperm Mitochondrial Function in Aging Roosters - PMC
Journal
Antioxidants (Basel, Switzerland)
S1PR3 inhibition protects against LPS-induced ARDS by inhibiting NF-B and improving mitochondrial oxidative phosphorylation - PMC
Journal
Journal of translational medicine
Loss of Paip1 causes translation reduction and induces apoptotic cell death through ISR activation and Xrp1 - PMC
Journal
Cell death discovery
Species
Drosophila melanogaster
Acute myeloid leukemia immune escape by epigenetic CD48 silencing
Journal
Clinical science (London, England : 1979)
Genome-wide CRISPR/Cas9 screen identifies SLC39A9 and PIK3C3 as crucial entry factors for Ebola virus infection - PMC
The Effects of Yeast Protein on Gut Microbiota in Mice When Compared with Soybean Protein and Whey Protein Isolates - PMC
SPG21, a potential oncogene targeted by miR-128-3p, amplifies HBx-induced carcinogenesis and chemoresistance via activation of TRPM7-mediated JNK pathway
Journal
Cellular oncology (Dordrecht)
Klf4 Promotes Dentinogenesis and Odontoblastic Differentiation via Modulation of TGF‐β Signaling Pathway and Interaction With Histone Acetylation
Journal
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Naringenin prevents TNF-α-induced gut-vascular barrier disruption associated with inhibiting the NF-κB-mediated MLCK/p-MLC and NLRP3 pathways
AXIN2 Reduces the Survival of Porcine Induced Pluripotent Stem Cells (piPSCs)
Targeting endometrial inflammation in intrauterine adhesion ameliorates endometrial fibrosis by priming MSCs to secrete C1INH - PMC
Species
Homo sapiens, Mus musculus
Exploring Ganweikang Tablet as a Candidate Drug for NAFLD Through Network Pharmacology Analysis and Experimental Validation - PMC
Journal
Frontiers in pharmacology
Berberine Reduces Aβ42 Deposition and Tau Hyperphosphorylation via Ameliorating Endoplasmic Reticulum Stress
Journal
Frontiers in pharmacology
The ALK1-Smad1/5-ID1 pathway participates in tumour angiogenesis induced by low-dose photodynamic therapy - PMC
Journal
International journal of oncology
Epigenetic silencing of LDHB promotes hepatocellular carcinoma by remodeling the tumor microenvironment - PMC
Journal
Cancer immunology, immunotherapy : CII
Exosomal CD44 Transmits Lymph Node Metastatic Capacity Between Gastric Cancer Cells via YAP-CPT1A-Mediated FAO Reprogramming
Journal
Frontiers in oncology
MiR-223-3p attenuates radiation-induced inflammatory response and inhibits the activation of NLRP3 inflammasome in macrophages
Journal
International immunopharmacology
TLR4 signalling: the key to controlling EV71 replication and inflammatory response - PMC
Journal
Frontiers in cellular and infection microbiology
Exploring the Underlying Mechanism of Ren-Shen-Bai-Du Powder for Treating Inflammatory Bowel Disease Based on Network Pharmacology and Molecular Docking - PMC
Journal
Pharmaceuticals (Basel, Switzerland)
Evodiamine induces ROS-Dependent cytotoxicity in human gastric cancer cells via TRPV1/Ca2+ pathway
Journal
Chem Biol Interact
The effects of dimethyl fumarate on cytoplasmic LPSinduced noncanonical pyroptosis in periodontal ligament fibroblasts and dental pulp cells
Journal
International endodontic journal
Unlocking therapeutic potential: dual gene therapy for ameliorating the disease phenotypes in a mouse model of RPE65 Leber congenital amaurosis - PMC
Journal
Frontiers in medicine
Natural astaxanthin enhanced antioxidant capacity and improved semen quality through the MAPK/Nrf2 pathway in aging layer breeder roosters
Journal
J Anim Sci Biotechnol
Species
Gallus gallus,Aves
Generation and characterization of a Müller-glial-cell-specific Il6ra knockout mouse to delineate the effects of IL-6 trans-signaling in the retina - PMC
Journal
Scientific reports
Melatonin administration alleviates 2, 2, 4, 4-tetra-brominated diphenyl ether (PBDE-47)-induced necroptosis and secretion of inflammatory factors via miR-140-5p …
Journal
Fish & shellfish immunology
Species
Oncorhynchus mykiss
Exosomal Small RNA Sequencing Profiles in Plasma from Subjects with Latent Mycobacterium tuberculosis Infection - PMC
miR-15b-5p promotes HgCl2-induced chicken embryo kidney cells ferroptosis by targeting -TrCP-mediated ATF4 ubiquitin degradation
Coordinated expression of p300 and HDAC3 upregulates histone acetylation during dentinogenesis
Journal
Journal of cellular biochemistry
N-Acetyl-L-Cysteine Ameliorates BPAF-Induced Porcine Sertoli Cell Apoptosis and Cell Cycle Arrest via Inhibiting the ROS Level - PMC
Neuroprotection of Resveratrol Against Focal Cerebral Ischemia/Reperfusion Injury in Mice Through a Mechanism Targeting Gut-Brain Axis.
Journal
Cellular and molecular neurobiology
Sirtuin 5-driven meiotic spindle assembly and actin-based migration in mouse oocyte meiosis - PMC
5-ALA-PDT induced ferroptosis in keloid fibroblasts via ROS, accompanied by downregulation of xCT, GPX4
Journal
Photodiagnosis and photodynamic therapy
Prolactin upregulates amino acids uptake in dairy cow mammary epithelial cells via LAT1
Journal
Journal of dairy science
A novel tumor suppressor CECR2 down regulation links glutamine metabolism contributes tumor growth in laryngeal squamous cell carcinoma
Antidepressant-like effects of cajaninstilbene acid and its related mechanisms in mice
Evodiamine induces reactive oxygen species‑dependent apoptosis and necroptosis in human melanoma A‑375 cells
Exploring and validating the metastasis mechanism of pathenolide interfering with cutaneous melanoma through ER stress‐dependent apoptosis based on the …
Journal
Phytochemical analysis : PCA
Echinacoside Protects Against Dysfunction of Spermatogenesis Through the MAPK Signaling Pathway
KCNH5 deletion increases autism susceptibility by regulating neuronal growth through Akt/mTOR signaling pathway
Journal
Behavioural brain research
LINC00974 sponges miR-33a to facilitate cell proliferation, invasion, and EMT of ovarian cancer through HMGB2 upregulation
Journal
Genetics and molecular biology
Podocyte SIRP reduction aggravates lupus nephritis via promoting T cell inflammatory responses
Species
Homo sapiens,Mus musculus
NLRP6 is required for cancer-derived exosome-modified macrophage M2 polarization and promotes metastasis in small cell lung cancer - PMC
Journal
Cell death & disease