EGFR core fucosylation, induced by hepatitis C virus, promotes TRIM40-mediated-RIG-I ubiquitination and suppresses interferon-I antiviral defenses - PMC
Journal
Nature communications
CircTmeff1 Promotes Muscle Atrophy by Interacting with TDP‐43 and Encoding A Novel TMEFF1‐339aa Protein
Journal
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Cytoplasmic Escape of Mitochondrial DNA Mediated by Mfn2 Downregulation Promotes Microglial Activation via cGasSting Axis in Spinal Cord Injury
Porcine reproductive and respiratory syndrome virus degrades DDX10 via SQSTM1/p62-dependent selective autophagy to antagonize its antiviral activity
STING signaling sensing of DRP1-dependent mtDNA release in kupffer cells contributes to lipopolysaccharide-induced liver injury in mice - PMC
Tumor-targeted Delivery of Copper-manganese Biomineralized Oncolytic Adenovirus for Colorectal Cancer Immunotherapy
Journal
Acta biomaterialia
mtDNA-cGAS-STING axis-dependent NLRP3 inflammasome activation contributes to postoperative cognitive dysfunction induced by sevoflurane in mice
Journal
International journal of biological sciences
DEAD-box RNA helicase 21 negatively regulates cytosolic RNA-mediated innate immune signaling - PMC
Journal
Frontiers in immunology
Seneca Valley Virus Suppresses Host Type I Interferon Production by Targeting Adaptor Proteins MAVS, TRIF, and TANK for Cleavage
Journal
Journal of Virology
UBR5 Acts as an Antiviral Host Factor against MERS-CoV via Promoting Ubiquitination and Degradation of ORF4b
Journal
Journal of virology
Lactate-lactylation-HSPA6 axis promotes PRRSV replication by impairing IFN- production
Journal
Journal of virology
Host protein, HSP90β, antagonizes IFN-β signaling pathway and facilitates the proliferation of encephalomyocarditis virus in vitro
Bovine viral diarrhea virus NS4B protein interacts with 2CARD of MDA5 domain and negatively regulates the RLR-mediated IFN-β production
CircSOBP suppresses the progression of glioma by disrupting glycolysis and promoting the MDA5-mediated immune response - PMC
Species
Homo sapiens, Mus musculus
Porcine Deltacoronavirus Accessory Protein NS7a Antagonizes IFN-β Production by Competing With TRAF3 and IRF3 for Binding to IKKε
Journal
Front Cell Infect Microbiol
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Membrane (M) and Spike (S) Proteins Antagonize Host Type I Interferon Response
Journal
Frontiers in cellular and infection microbiology
HSP27 Attenuates cGAS-Mediated IFN-β Signaling through Ubiquitination of cGAS and Promotes PRV Infection - PMC
Loss of ZNF408 attenuates STING-mediated immune surveillance in breast carcinogenesis - PMC
Loss of ZNF408 attenuates STING-mediated immune surveillance in breast carcinogenesis - PMC
Activation of STING by the Novel Liposomal TLC388 Enhances the Therapeutic Response to Anti-PD-1 Antibodies in Combination with Radiotherapy
Journal
Cancer immunology, immunotherapy : CII
A role of STING signaling in obesity-induced lung inflammation - PMC
Journal
International journal of obesity (2005)
Hyperacetylated microtubules assist porcine deltacoronavirus nsp8 to degrade MDA5 via SQSTM1/p62-dependent selective autophagy - PMC
Journal
Journal of virology
Isolation of Limosilactobacillus mucosae G01 with inhibitory effects on porcine epidemic diarrhea virus in vitro from Bama pig gastroenteritis - PMC
Journal
Frontiers in microbiology
CircELK4 Contributes to Lupus Nephritis by Acting as a miR-27b-3p Sponge to Regulate STING/IRF3/IFN-I Signaling
Species
Homo sapiens, Mus musculus
Porcine deltacoronavirus nsp15 antagonizes interferon-β production independently of its endoribonuclease activity.
Journal
Molecular Immunology
The reverse transcriptase inhibitor 3TC modulates hippocampal transcriptome signatures of inflammation in tauopathy model mice - PMC
Journal
Experimental gerontology
Porcine deltacoronavirus nsp10 antagonizes interferon-β production independently of its zinc finger domains
Pol modulates the expression of type I interferon via STING pathway
Journal
Biochemical and biophysical research communications
PI3K/AKT mediated De novo fatty acid synthesis regulates RIG-1/MDA-5-dependent type I IFN responses in BVDV-infected CD8+ T cells
Journal
Veterinary microbiology