Foot-and-mouth disease virus VP1 degrades YTHDF2 through autophagy to regulate IRF3 activity for viral replication
Species
Homo sapiens,Sus scrofa
Sialic acid-based probiotic intervention in lactating mothers improves the neonatal gut microbiota and immune responses by regulating sialylated milk oligosaccharide synthesis via the gut-breast axis - PMC
P-Glycoprotein Aggravates Blood Brain Barrier Dysfunction in Experimental Ischemic Stroke by Inhibiting Endothelial Autophagy - PMC
Sitravatinib as a potent FLT3 inhibitor can overcome gilteritinib resistance in acute myeloid leukemia - PMC
Journal
Biomarker research
Nicotine restores olfactory function by activation of prok2R/Akt/FoxO3a axis in Parkinsons disease - PMC
Journal
Journal of translational medicine
Chinese Sumac Fruits (Rhus chinesis Mill.) Alleviate Type 2 Diabetes in C57BL/6 Mice through Repairing Islet Cell Functions, Regulating IRS-1/PI3K/AKT Pathways and Promoting the Entry of Nrf2 into the Nucleus - PMC
Galangin inhibits neointima formation induced by vascular injury via regulating the PI3K/AKT/mTOR pathway
Blue light impairs cornea and corneal wound healing by downregulating VCAM1 partly - PMC
Species
Oryctolagus cuniculus
Alternative glucose uptake mediated by -catenin/RSK1 axis under stress stimuli in mammalian cells
Journal
Biochemical pharmacology
An epithelial-mesenchymal plasticity signature identifies two novel LncRNAs with the opposite regulation - PMC
Journal
Frontiers in cell and developmental biology
Gypenoside IX restores Akt/GSK-3 pathway and alleviates Alzheimers disease-like neuropathology and cognitive deficits - PMC
CD30 plays a role in Tdependent immune response and T cell proliferation
Journal
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
NONO regulates B‐cell development and B‐cell receptor signaling
Journal
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
Benzo [b] fluoranthene induces male reproductive toxicity and apoptosis via Akt-Mdm2-p53 signaling axis in mouse Leydig cells: Integrating computational toxicology
Journal
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
The Protective Effect and Mechanism of a Phytochemical Extract from the Wild Vegetable Shutou (Crateva unilocularis Buch.) against Acetaminophen-Induced Liver Injury in Mice - PMC
Journal
Foods (Basel, Switzerland)
Atractylenolide III Ameliorated Autophagy Dysfunction via Epidermal Growth Factor Receptor-Mammalian Target of Rapamycin Signals and Alleviated Silicosis
Journal
Laboratory investigation; a journal of technical methods and pathology
The water-soluble subfraction from Artemisia argyi alleviates LPS-induced inflammatory responses via multiple pathways and targets in vitro and in vivo
Journal
Journal of ethnopharmacology
Inhibition of TNBC Cell Growth by Paroxetine: Induction of Apoptosis and Blockage of Autophagy Flux - PMC
ANLN Promotes the Proliferation and Migration of Gallbladder Cancer Cells via STRA6-Mediated Activation of PI3K/AKT Signaling
Tetrahydroalstonine possesses protective potentials on palmitic acid stimulated SK-N-MC cells by suppression of A1-42 and tau through regulation of PI3K/Akt
Journal
European journal of pharmacology
Tetrahydroalstonine possesses protective potentials on palmitic acid stimulated SK-N-MC cells by suppression of A1-42 and tau through regulation of PI3K/Akt
Journal
European journal of pharmacology
Isocitrate dehydrogenase 2 regulates the proliferation of triple-negative breast cancer through the ferroptosis pathway - PMC
Journal
Scientific reports
Prognostic and functional roles of EIF4G1 in lung squamous cell carcinoma - PMC
UHMK1 promotes lung adenocarcinoma oncogenesis by regulating the PI3K/AKT/mTOR signaling pathway
Autophagy inhibition mediated by trillin promotes apoptosis in hepatocellular carcinoma cells via activation of mTOR/STAT3 signaling
Journal
Naunyn-Schmiedeberg's archives of pharmacology
Deciphering the role of TNF--induced protein 8-like 2 in the pathogenesis of necrotizing enterocolitis in neonatal rats - PMC
Journal
Experimental and therapeutic medicine
Mitochondrial transplantation inhibits cholangiocarcinoma cells growth by balancing oxidative stress tolerance through PTEN/PI3K/AKT signaling pathway
Mechanism of regulation of KIF23 on endometrial cancer cell growth and apoptosis.
Journal
Discover. Oncology