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Rabbit anti-Sheep IL-6 mAb(CAP) (RM17804)

This standard curve is only for demonstration purposes. A standard curve should be generated for eachassay.

Fromthe comparison of the standard curve, it is found that ABclonal has highsensitivity.

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货号: RM17804
促销价:   ¥2100
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详细信息

产品名称
Rabbit anti-Sheep IL-6 mAb(CAP)
货号
RM17804
免疫原
Recombinant Sheep IL-6
纯化方式
Affinity purification
同种型
Rabbit IgG
存储溶液
Supplied as a 0.2um filtered solution in PBS with 0.05%ProClin 300,PH 7.4.
CrossReactivity
No cross-reactivity in ELISA assay withrecombinant
Human IL-6、Mouse IL-6、Rat IL-6
存储条件
Store at -20℃. Avoid freeze / thaw cycles. Preservative:0.05%ProClin 300.Avoid repeated freeze-thaw cycles.

* This package insert must be read in its entirety before using this product.

应用

Sheep IL-6 Sandwich ELISA Immunoassay

 Recommended
Concentration
Sample
ELISA Capture0.25-1ug/mLRabbit anti-Sheep IL-6 (CAP)(Cat. No.RM17804)
ELISA Detection0.08-0.02ug/mLRabbit anti-Sheep IL-6 (DET)(Cat. No.RM17805)
Standard15.6-1000pg/mLRecombinant Sheep IL-6 Protein

背景信息

Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway. The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.By Similarity IL6 is a potent inducer of the acute phase response. Rapid production of IL6 contributes to host defense during infection and tissue injury, but excessive IL6 synthesis is involved in disease pathology.

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