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Human VCAM-1 Sandwich ELISA Immunoassay
Recommended Concentration | Sample | |
---|---|---|
ELISA Capture | 1-4ug/mL | Rabbit anti-Human VCAM-1 mAb(CAP)(Cat. No.RMK0013) |
ELISA Detection | 0.125-0.5ug/mL | Rabbit anti-Human VCAM-1 mAb(DET)(Cat. No.RMK0014) |
Standard | 15.63-1000pg/mL | RecombinantHuman VCAM-1 Protein(Cat. No.RP00972) |
Cell adhesion glycoprotein predominantly expressed on the surface of endothelial cells that plays an important role in immune surveillance and inflammation (PubMed:31310649).Acts as a major regulator of leukocyte adhesion to the endothelium through interaction with different types of integrins (PubMed:10209034).During inflammatory responses, binds ligands on the surface of activated endothelial cells to initiate the activation of calcium channels and the plasma membrane-associated small GTPase RAC1 leading to leukocyte transendothelial migration