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Human IL-13 multiplex assay
Recommended Concentration | Sample | |
---|---|---|
Multiplex Capture | 3-20ug/mL | Rabbit anti-Human IL-13 mAb(Cat. No.RMK0199) |
Multiplex Detection | 0.017-2ug/mL | Rabbit anti-Human IL-13 mAb(Cat. No.RMK0200) |
Standard | 6.86-5000pg/mL | Recombinant Human IL-13 Protein |
This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4.