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Rabbit anti-Human EPOR mAb (RMK0270)

This standard curve is only for demonstration purposes. A standard curve should be generated for eachassay.

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货号: RMK0270
促销价:   ¥2100
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详细信息

产品名称
Rabbit anti-Human EPOR mAb
货号
RMK0270
免疫原
Recombinant human EPOR
纯化方式
Affinity purification
同种型
Rabbit IgG
内毒素水平
/
存储溶液
Supplied as a 0.2 μm filtered solution in PBS with 0.05% Proclin 300, pH 7.4.
CrossReactivity
/
存储条件
Store at -20℃.Avoid repeated freeze-thaw cycles.

* This package insert must be read in its entirety before using this product.

应用

Human EPOR Sandwich Immunoassay

 Recommended
Concentration
Sample
ELISA Capture1-4 μg/mLRabbit anti-Human EPOR mAb (Cat. No. RMK0270)
ELISA Detection0.002-0.008 μg/mLRabbit anti-Human EPOR mAb (Cat. No. RMK0271)
Standard31.25-2000 pg/mLRecombinant Human Erythropoietin R/EPO-R Protein (Cat. No. RP00111)

背景信息

This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.