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* This package insert must be read in its entirety before using this product.
Human IL-31 Sandwich Immunoassay
| Recommended Concentration | Sample | ||
|---|---|---|---|
| Multiplex | Capture | 3-20ug/mL | Rabbit anti-Human IL-31 mAb(Cat. No.RMK0319) |
| Detection | 0.017-2ug/mL | Rabbit anti-Human IL-31 mAb(Cat. No.RMK0320) | |
| Standard | 6.86-5000pg/mL | Recombinant Human IL-31 Protein |
IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]).
