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Human CA125/MUC16 multiplex assay
| Recommended Concentration | Sample | |
|---|---|---|
| Multiplex Capture | 3-20ug/mL | Rabbit anti-Human CA125/MUC16 mAb(Cat. No.RMK0330) |
| Multiplex Detection | 0.017-2ug/mL | Rabbit anti-Human CA125/MUC16 mAb(Cat. No.RMK0331) |
| Standard | 6.86-5000pg/mL | Recombinant Human CA125/MUC16 Protein |
The CA125 antigen, also known as MUC16, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy. Expression of isoforms, proteolytic cleavage, and heavy N- and O- linked glycosylation produce forms of human CA125 that can vary from 200-5000 kDa in size. It inhibits NK cell activity, which is thought to contribute to immune evasion in peritoneal cancer and pregnancy.
