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Recombinant Human UBE2L3 Protein (RP00025LQ)

Recombinant Human UBE2L3 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 19 kDa.

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货号: RP00025LQ
促销价:   ¥2000
货    期:现货产品
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详细信息

种属
Human
表达宿主
E. coli
Calculated MW
18.70 kDa
Observed MW
18-20 kDa
标签
C-His
纯度
> 95% by SDS-PAGE.
内毒素
Please contact us for more information.
制剂
Supplied in 50mM HEPES,200mM NaCl,10%glycerol,1mM TCEP,pH 7.0Contact us for customized product form or formulation.
描述
Recombinant Human UBE2L3 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Met1-Asp154) of human UBE2L3 (Accession #NP_003338.1) fused with a 6×His tag at the C-terminus.
储存
Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles.未开盖的干粉蛋白在 -20°C至-80°C可保存12个月;
复溶之后,蛋白溶液在-20°C及以下可保存3个月,在2-8℃可保存1周。

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请在蛋白复溶计算器中输入蛋白总质量和所需终浓度,快速计算您需要添加溶液的体积吧!
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背景信息

Ubiquitin-conjugating Enzyme E2L 3 (UBE2L3),also known as Ubiquitin-conjugating Enzyme H7 (UbcH7), is a member of the Ubiquitin-conjugating (E2) enzyme family (1). The human UbcH7 protein shares 100% amino acid (aa) sequence identity with the mouse and rat orthologs. UBE2L3 is catalytically active with HECT and RBR domain-containing families of Ubiquitin ligases (E3s). UBE2L3 localizes to both the nucleus and cytoplasm in human cells. UBE2L3 depletion results in an extended S phase and a reduced rate of proliferation, suggesting that it may play a role in the cell cycle. In humans, single nucleotide polymorphisms in UBE2L3 are associated with systemic lupus erythematosus and Crohn's disease, suggesting that UbcH7 is important for proper immune system function.

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