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Mouse vascular endothelial growth factor D, (VEGFD) is a member of the platelet-derived growthfactor/vascular endothelial growth factor (PDGF/VEGF) family. VEGFD is a secreted protein and highlyexpressed in fetal and adult lung. It undergoes a complex proteolytic maturation, generating multipleprocessed forms that bind and activate VEGFR-2 and VEGFR-3 receptors. The structure and function of thisprotein is similar to VEGFC. VEGFD is growth factor which active in angiogenesis, lymphangiogenesis, andendothelial cell growth, stimulating their proliferation and migration and also has effects on the permeabilityof blood vessels.