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Recombinant Human Claudin-4 Protein (RP02997LQ)

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The purity of Human Claudin-4 VLP is greater than 95% as determined by SEC-HPLC.

Immobilized Human Claudin-4 VLP at 1μg/ml (100μl/well) on the plate. Dose response curve for Anti-Claudin 4 Antibody, hFc Tag with the EC50 of 18.4ng/ml determined by ELISA.

All(2)|
货号: RP02997LQ
促销价：   ￥10500
货    期：现货产品
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详细信息

种属
Human
表达宿主
HEK293 cells
描述
Recombinant Human Claudin-4 Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Met1-Val209) of human Claudin-4 (Accession #NP_001296.1 ) fused with no additional amino acid.
标签
No tag
纯度
> 95% as determined by HPLC
内毒素
Less than 1EU per μg by the LAL method.
生物活性
Immobilized Human Claudin-4 VLP at 1μg/ml (100μl/well) on the plate. Dose response curve for Anti-Claudin 4 Antibody, hFc Tag with the EC50 of 18.4ng/ml determined by ELISA.
制剂
Supplied as 0.22μm filtered solution in PBS (pH 7.4). Notice: If you need it for immunization, Do Not use any adjuvant.
储存
Valid for 12 months from date of receipt when stored at -80°C.Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.未开盖的干粉蛋白在 -20°C至-80°C可保存12个月；
复溶之后，蛋白溶液在-20°C及以下可保存3个月，在2-8℃可保存1周。

蛋白复溶计算器

请在蛋白复溶计算器中输入蛋白总质量和所需终浓度，快速计算您需要添加溶液的体积吧！
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背景信息

Claudin-4 (CLDN4) is a key component of tight junctions (TJs) in epithelial cells. CLDN4 is overexpressed in many epithelial malignancies and correlates with cancer progression. Changes in CLDN4 expression have been associated with epigenetic factors (such as hypomethylation of promoter DNA), inflammation associated with infection and cytokines, and growth factor signaling. CLDN4 helps to maintain the tumor microenvironment by forming TJs and acts as a barrier to the entry of anticancer drugs into tumors.

基因ID
1364
Swiss Prot
O14493
别名
Claudin-4; CLDN4; Claudin4; CPE-R; CPE R; CPETR1; WBSCR8
研究领域
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