Targeting ferroptosis by poly(acrylic) acid coated Mn3O4 nanoparticles alleviates acute liver injury - PMC
Journal
Nature communications
Species
Homo sapiens,Mus musculus
Regulation of micro- and small-exon retention and other splicing processes by GRP20 for flower development - PMC
Species
Arabidopsis thaliana
FERONIA coordinates plant growth and salt tolerance via the phosphorylation of phyB
Species
Arabidopsis thaliana, Oryza sativa
Parabacteroides distasonis regulates the infectivity and pathogenicity of SVCV at different water temperatures - PMC
Cu2WS4PEG Nanozyme as Multifunctional Sensitizers for Enhancing ImmunoRadiotherapy by Inducing Ferroptosis
Journal
Small (Weinheim an der Bergstrasse, Germany)
Obstructive Sleep Apnea Syndrome Exacerbates NASH Progression via Selective AutophagyMediated Eepd1 Degradation
Journal
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Targeting Nr2e3 to Modulate Tet2 Expression: Therapeutic Potential for Depression Treatment
Journal
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Polyacrylic AcidCoated SeleniumDoped Carbon Dots Inhibit Ferroptosis to Alleviate ChemotherapyAssociated Acute Kidney Injury
Journal
Advanced science (Weinheim, Baden-Wurttemberg, Germany)
PD-L1 methylation restricts PD-L1/PD-1 interactions to control cancer immune surveillance - PMC
PD-L1 methylation restricts PD-L1/PD-1 interactions to control cancer immune surveillance - PMC
A regulatory module comprising G3BP1-FBXL5-IRP2 axis determines sodium arsenite-induced ferroptosis
Journal
Journal of hazardous materials
Arabidopsis Transcription Factor Wrky45 Confers Cadmium Tolerance Via Activating Pcs1 and Pcs2 Expression
Journal
Journal of hazardous materials
Species
Arabidopsis thaliana
Efficient synthesis of squalene by cytoplasmic-peroxisomal engineering and regulating lipid metabolism in Yarrowia lipolytica
Journal
Bioresource technology
Species
Saccharomyces cerevisiae
Exosomal miRNA-26b-5p from PRP suppresses NETs by targeting MMP-8 to promote diabetic wound healing
Journal
Journal of controlled release : official journal of the Controlled Release Society
Species
Homo sapiens,Mus musculus
AIM2 promotes renal cell carcinoma progression and sunitinib resistance through FOXO3a-ACSL4 axis-regulated ferroptosis - PMC
Journal
International journal of biological sciences
Tetrandrine synergizes with MAPK inhibitors in treating KRAS-mutant pancreatic ductal adenocarcinoma via collaboratively modulating the TRAIL-death
Journal
Pharmacological research
Oroxylin A regulates cGAS DNA hypermethylation induced by methionine metabolism to promote HSC senescence
Journal
Pharmacological research
Pralatrexate inhibited the replication of varicella zoster virus and vesicular stomatitis virus: An old dog with new tricks
Journal
Antiviral research
Species
Varicella zoster virus, Varicella zoster virus
Remodeling tumor-associated macrophage for anti-cancer effects by rational design of irreversible inhibition of mitogen-activated protein kinase-activated protein kinase 2 - PMC
SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway
Controllable Fabrication of Highly Ordered Spherical Microcavity Arrays by Replica Molding of In Situ Self-Emulsified Droplets
Journal
ACS applied materials & interfaces
Controllable Fabrication of Highly Ordered Spherical Microcavity Arrays by Replica Molding of In Situ Self-Emulsified Droplets
Journal
ACS applied materials & interfaces
Multi-omics data reveals aberrant gut microbiota-host glycerophospholipid metabolism in association with neuroinflammation in APP/PS1 mice
Hedgehog signaling regulates bone homeostasis through orchestrating osteoclast differentiation and osteoclastosteoblast coupling
Journal
Cellular and molecular life sciences : CMLS
Selenite Bioremediation by Food-Grade Probiotic Lactobacillus casei ATCC 393: Insights from Proteomics Analysis
Journal
Microbiology spectrum
Targeting METTL3 reprograms the tumor microenvironment to improve cancer immunotherapy
Journal
Cell chemical biology
Species
Homo sapiens,Mus musculus
Bisphenol C induces developmental defects in liver and intestine through mTOR signaling in zebrafish (Danio rerio)
Letrozole induced a polycystic ovary syndrome model in zebrafish by interfering with the hypothalamic-pituitary-gonadal axis
Journal
Environmental pollution (Barking, Essex : 1987)
Transcriptional profile of human thymus reveals IGFBP5 is correlated with age-related thymic involution - PMC
Journal
Frontiers in immunology
The haplotype-resolved genome assembly of autotetraploid rhubarb Rheum officinale provides insights into the genome evolution and massive accumulation of
Journal
Plant communications
Species
Rheum officinale Baill
EXO1/P53/SREBP1 axis-regulated lipid metabolism promotes prostate cancer progression - PMC
Journal
Journal of translational medicine
Sestrin2 reduces ferroptosis via the Keap1/Nrf2 signaling pathway after intestinal ischemia-reperfusion
Journal
Free radical biology & medicine
ALDH2 deficiency exacerbates MCD-diet induced MASLD by modulating bile acid metabolism
Journal
Free radical biology & medicine
Development of nanobodies against Staphylococcus enterotoxin B through yeast surface display
Journal
International journal of biological macromolecules
De novo design of a protein binder against Staphylococcus enterotoxin B
Journal
International journal of biological macromolecules
Antibacterial Property and Mechanisms of Au@Ag Core-Shell Nanoparticles with Near-Infrared Absorption Against E. faecalis Infection of Dentin - PMC
Journal
International journal of nanomedicine
Species
Arabidopsis thaliana
Magnolol against enterovirus 71 by targeting Nrf2-SLC7A11-GSH pathway
Journal
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Interactome between ASFV and host immune pathway proteins
The lack of PPAR exacerbated the progression of non-alcoholic steatohepatitis in mice with spleen deficiency syndrome by triggering an inflammatory response - PMC
Journal
Frontiers in immunology
X-box binding protein 1 caused an imbalance in pyroptosis and mitophagy in immature rats with di-(2-ethylhexyl) phthalate-induced testis toxicity
Glycogen metabolism reprogramming promotes inflammation in coal dust-exposed lung
Journal
Ecotoxicology and environmental safety
2-Deoxy-D-glucose ameliorates inflammation and fibrosis in a silicosis mouse model by inhibiting hypoxia-inducible factor-1 in alveolar macrophages
Journal
Ecotoxicology and environmental safety
Metabolic and microbial mechanisms related to the effects of dietary wheat levels on intramuscular fat content in finishing pigs
CSGALNACT2 restricts ovarian cancer migration and invasion by modulating MAPK/ERK pathway through DUSP1
Journal
Cellular oncology (Dordrecht)
Gain‐of‐function of progesterone receptor membrane component 2 ameliorates ischemic brain injury
Journal
CNS neuroscience & therapeutics
Identification and Validation of the miR/RAS/RUNX2 Autophagy Regulatory Network in AngII-Induced Hypertensive Nephropathy in MPC5 Cells Treated with Hydrogen Sulfide Donors - PMC
Journal
Antioxidants (Basel, Switzerland)
Beneficial impact of cardiac heavy metal scavenger metallothionein in sepsis-provoked cardiac anomalies dependent upon regulation of endoplasmic reticulum stress
RACK1 enhances STAT3 stability and promotes T follicular helper cell development and function during blood-stage Plasmodium infection in mice - PMC
Rosa Roxburghii Tratt Fruit Extract Prevents Dss-Induced Ulcerative Colitis in Mice by Modulating the Gut Microbiota and the IL-17 Signaling Pathway - PMC
Rosa Roxburghii Tratt Fruit Extract Prevents Dss-Induced Ulcerative Colitis in Mice by Modulating the Gut Microbiota and the IL-17 Signaling Pathway - PMC
Nicotinamide Mononucleotide Ameliorates Silica-Induced Lung Injury through the Nrf2-Regulated Glutathione Metabolism Pathway in Mice - PMC
Genome-wide analysis of transcriptome and histone modifications in Brassica napus hybrid - PMC
Journal
Frontiers in plant science
Hexokinase1: A Glucose Sensor Involved in Drought Stress Response and Sugar Metabolism Depending on Its Kinase Activity in Strawberry
Journal
Frontiers in plant science
Integration of ATAC-seq and RNA-seq analysis identifies key genes affecting intramuscular fat content in pigs - PMC
Journal
Frontiers in nutrition
ASH2L mediates epidermal differentiation and hair follicle morphogenesis via H3K4me3 modification
Journal
The Journal of investigative dermatology
Lactobacillus-derived protoporphyrin IX and SCFAs regulate the fiber size via glucose metabolism in the skeletal muscle of chickens
Atractylodin targets GLA to regulate Dmannose metabolism to inhibit osteogenic differentiation of human valve interstitial cells and ameliorate aortic valve
Journal
Phytotherapy research : PTR
Atractylenolide‐1 affects glycolysis/gluconeogenesis by downregulating the expression of TPI1 and GPI to inhibit the proliferation and invasion of human triple …
Journal
Phytotherapy research : PTR
PARM1 Drives Smooth Muscle Cell Proliferation in Pulmonary Arterial Hypertension via AKT/FOXO3A Axis - PMC
Journal
International journal of molecular sciences
Species
Mus musculus, Rattus norvegicus
Genome-Wide Comprehensive Analysis of the Nitrogen Metabolism Toolbox Reveals Its Evolution and Abiotic Stress Responsiveness in Rice (Oryza sativa L.) - PMC
Journal
International journal of molecular sciences
Cytoophidia Influence Cell Cycle and Size in Schizosaccharomyces pombe - PMC
Journal
International journal of molecular sciences
Species
Saccharomyces cerevisiae
TonEBP: A Key Transcription Factor in Microglia Following Intracerebral Hemorrhage Induced-Neuroinflammation - PMC
Journal
International journal of molecular sciences
Drosophila melanogaster Transcriptome Response to Different Wolbachia Strains - PMC
Journal
International journal of molecular sciences
Bacteroides-derived isovaleric acid enhances mucosal immunity by facilitating intestinal IgA response in broilers - PMC
Journal
Journal of animal science and biotechnology
-Nicotinamide Mononucleotide Supplementation Prolongs The Lifespan Of Premature Ageing Mice And Protects Colon Function In Ageing Mice
Theabrownin as a Potential Prebiotic Compound Regulates Lipid Metabolism via the Gut Microbiota, Microbiota-Derived Metabolites, and Hepatic FoxO/PPAR
Journal
Journal of agricultural and food chemistry
JUN mediates glucocorticoid resistance by stabilizing HIF1a in T cell acute lymphoblastic leukemia - PMC
Hepatic ZBTB22-mediated detoxification ameliorates acetaminophen-induced liver injury by inhibiting pregnane X receptor signaling - PMC
Establishment of highly metastatic ovarian cancer model with omental tropism via in vivo selection - PMC
GSDMA3 deficiency reprograms cellular metabolism and modulates BCR signaling in murine B cells - PMC
Degradation of Alginate by a Newly Isolated Marine Bacterium Agarivorans sp. B2Z047
Astragalus polysaccharides alleviates lipopolysaccharides-induced inflammatory lung injury by altering intestinal microbiota in mice - PMC
Journal
Frontiers in microbiology
Dapagliflozin alleviates myocardial ischemia/reperfusion injury by reducing ferroptosis via MAPK signaling inhibition - PMC
Journal
Frontiers in pharmacology
Valsartan attenuates LPS-induced ALI by modulating NF-B and MAPK pathways - PMC
Journal
Frontiers in pharmacology
Ganfule capsule alleviates bile duct ligation-induced liver fibrosis in mice by inhibiting glutamine metabolism - PMC
Journal
Frontiers in pharmacology
Antibiotic-Induced Gut Microbial Dysbiosis Reduces the Growth of Weaning Rats via FXR-Mediated Hepatic IGF-2 Inhibition - PMC
A CRISPR/Cas9 screen in embryonic stem cells reveals that Mdm2 regulates totipotency exit - PMC
Journal
Communications biology
Retinoic AcidPPAR Mediates -Carotene Resistance to Placental Dysfunction Induced by Deoxynivalenol
Journal
Journal of agricultural and food chemistry
DDX19A promotes gastric cancer cell proliferation and migration by activating the PI3K/AKT pathway - PMC
Journal
Cancer cell international
TGFBI promotes proliferation and epithelial-mesenchymal transition in renal cell carcinoma through PI3K/AKT/mTOR/HIF-1 pathway - PMC
Journal
Cancer cell international
Dual roles of HK3 in regulating the network between tumor cells and tumor-associated macrophages in neuroblastoma - PMC
Journal
Cancer immunology, immunotherapy : CII
Forsythiaside A suppresses renal fibrosis and partial epithelial-mesenchymal transition by targeting THBS1 through the PI3K/AKT signaling pathway
Journal
International immunopharmacology
Cold-inducible RNA-binding protein induces inflammatory responses via NF-B signaling pathway in normal human bronchial epithelial cells infected with
Journal
International immunopharmacology
PCSK9 inhibitor protects against ischemic cerebral injury by attenuating inflammation via the GPNMB/CD44 pathway
Journal
International immunopharmacology
Knockdown of EIF4G1 in NSCLC induces CXCL8 secretion - PMC
Journal
Frontiers in pharmacology
Plantaginis Semen Ameliorates Hyperuricemia Induced by Potassium Oxonate - PMC
Journal
International journal of molecular sciences
A novel Senescence-Based prognostic model unveils tumor interactions and drug resistance in colorectal cancer
Journal
International immunopharmacology
Genome-Wide Analysis of the Oat (Avena sativa) HSP90 Gene Family Reveals Its Identification, Evolution, and Response to Abiotic Stress - PMC
Journal
International journal of molecular sciences
Baicalin Weakens the Virulence of Porcine Extraintestinal Pathogenic Escherichia coli by Inhibiting the LuxS/AI-2 Quorum-Sensing System - PMC
GhMYC1374 regulates the cotton defense response to cotton aphids by mediating the production of flavonoids and free gossypol
Journal
Plant physiology and biochemistry : PPB
Species
Gossypium hirsutum L
GRP78 recognizes EV-F 3D protein and activates NF-B to repress virus replication by interacting with CHUK/IKBKB
Journal
Journal of virology
Species
Chlorocebus aethiops
IDO1 Inhibitor RY103 Suppresses Trp-GCN2-Mediated Angiogenesis and Counters Immunosuppression in Glioblastoma - PMC
An intranasal influenza virus vector vaccine protects against Helicobacter pylori in mice
Journal
Journal of virology
Effects of Probiotic Enterococcus faecium from Yak on the Intestinal Microflora and Metabolomics of Mice with Salmonella Infection
Journal
Probiotics and antimicrobial proteins
Soybean PHR1-regulated low phosphorus-responsive GmRALF22 increases uptake of phosphate via stimulating GmPTs expression
Journal
Plant science : an international journal of experimental plant biology
Ginsenoside Rg1 regulates thiram-induced chondrocytes' apoptosis and angiogenesis in broiler chickens
Journal
Environmental science and pollution research international
Bi-allelic variants in ASTL cause abnormal fertilization or oocyte maturation defects
Journal
Human molecular genetics
Exosomal NAT10 from esophageal squamous cell carcinoma cells modulates macrophage lipid metabolism and polarization through ac4C modification of FASN - PMC
Journal
Translational oncology
A low-cost, portable, dual-function readout device for amplification-based point-of-need diagnostics
Journal
Applied and environmental microbiology
Species
Fusarium oxysporum f. sp. conglutinans, Pseudomonas syringae pv. tomato DC3000, Theobroma cacao
Atractylenolide III Ameliorates Bile Duct Ligation-Induced Liver Fibrosis by Inhibiting the PI3K/AKT Pathway and Regulating Glutamine Metabolism - PMC
Journal
Molecules (Basel, Switzerland)
TMT-Based Proteomics Reveal the Mechanism of Action of Amygdalin against Rheumatoid Arthritis in a Rat Model through Regulation of Complement and Coagulation Cascades - PMC
Journal
Molecules (Basel, Switzerland)
SH2D4A inhibits esophageal squamous cell carcinoma progression through FAK/PI3K/AKT signaling pathway
Journal
Cellular signalling
Ghrelin alleviates intestinal ischemiareperfusion injury by activating the GHSR1/Sirt1/FOXO1 pathway
Journal
FASEB journal : official publication of the Federation of American Societies for Experimental Biology
PAIP2 is a potential diagnostic and prognostic biomarker of breast cancer and is associated with immune infiltration - PMC
Journal
Frontiers in genetics
Analysis of the potential ferroptosis mechanism and multitemporal expression change of central ferroptosis-related genes in cardiac ischemia-reperfusion injury - PMC
Journal
Frontiers in physiology
Analysis and Validation of Critical Signatures and Immune Cell Infiltration Characteristics in Doxorubicin-Induced Cardiotoxicity by Integrating Bioinformatics and Machine Learning - PMC
Journal
Journal of inflammation research
Vitamin D3 can effectively and rapidly clear largemouth bass ranavirus by immunoregulation
Journal
Fish & shellfish immunology
Species
Micropterus salmoides
Moderate mechanical stress suppresses chondrocyte ferroptosis in osteoarthritis by regulating NF-B p65/GPX4 signaling pathway - PMC
Journal
Scientific reports
Ferritinophagy-Mediated Hippocampus Ferroptosis is Involved in Cognitive Impairment in Immature Rats Induced by Hypoxia Combined with Propofol
Journal
Neurochemical research
Pasteurella multocida activates apoptosis via the FAK-AKT-FOXO1 axis to cause pulmonary integrity loss, bacteremia, and eventually a cytokine storm - PMC
Journal
Veterinary research
Lactiplantibacillus plantarum postbiotic protects against Salmonella infection in broilers via modulating NLRP3 inflammasome and gut microbiota - PMC
Polygonum Cuspidatum Alcohol Extract Exerts Analgesic Effects via the MAPK/ERK Signaling Pathway - PMC
Journal
Drug design, development and therapy
Resveratrol and (-)-Epigallocatechin-3-gallate Regulate Lipid Metabolism by Activating the AMPK Pathway in Hepatocytes - PMC
Resveratrol and (-)-Epigallocatechin-3-gallate Regulate Lipid Metabolism by Activating the AMPK Pathway in Hepatocytes - PMC
Baicalein Inhibits the Staphylococcus aureus Biofilm and the LuxS/AI-2 System in vitro - PMC
Journal
Infection and drug resistance
Lotus leaf extract can attenuate salpingitis in laying hens by inhibiting apoptosis
Dietary bile acids supplementation improves the growth performance and alleviates fatty liver in broilers fed a high-fat diet via improving the gut microbiota
A Model to Predict Prognosis of Renal Cell Clear Cell Carcinoma Based on 3 Angiogenesis-related Long Non-coding RNAs - PMC
A novel model of urosepsis in mice developed by ureteral ligation and injection of Escherichia coli into the renal pelvis - PMC
Unveiling the Regulatory Role of SIRT1 in Oxidative Stress Response of bovine mammary cells
Journal
Journal of dairy science
p39 Affects Myelin Formation in Cerebral Ischemic Injury
Journal
Neuromolecular medicine
Impact of cell-free supernatant of lactic acid bacteria on Staphylococcus aureus biofilm and its metabolites - PMC
Journal
Frontiers in veterinary science
VdTps2 modulates plant colonization and symptom development in Verticillium dahliae
Journal
Molecular plant-microbe interactions : MPMI
RICH1 is a novel key suppressor of isoproterenol- or angiotensin II-induced cardiomyocyte hypertrophy - PMC
Journal
Molecular medicine reports
CLIP170 inhibits the metastasis and EMT of papillary thyroid cancer through the TGF- pathway
Journal
Medical oncology (Northwood, London, England)
DJC78 is a cochaperone that interacts with cpHsc70-1 in the chloroplasts
Journal
Biochemical and biophysical research communications
Species
Arabidopsis thaliana
Parental betaine supplementation promotes gosling growth with epigenetic modulation of IGF gene family in the liver
Journal
Journal of animal science
PERP may affect the prognosis of lung adenocarcinoma by inhibiting apoptosis
Journal
Cancer management and research
Impacts of Dietary Standardized Ileal Digestible Lysine to Net Energy Ratio on Lipid Metabolism in Finishing Pigs Fed High-Wheat Diets - PMC
Journal
Animals : an open access journal from MDPI
Unraveling the pathogenic potential of the Pentatrichomonas hominis PHGD strain: impact on IPEC-J2 cell growth, adhesion, and gene expression
Journal
Parasite (Paris, France)
Identification and validation of an endoplasmic-reticulum-stress-related gene signature as an effective diagnostic marker of endometriosis
Role of Kinetochore Scaffold 1 (KNL1) in Tumorigenesis and Tumor Immune Microenvironment in Pan-Cancer: Bioinformatics Analyses and Validation of Expression - PMC
Journal
International journal of general medicine
USP54 is a potential therapeutic target in castration-resistant prostate cancer - PMC
Fertility differences between two wild-type
Drosophila melanogaster lines correlate
with differences in the expression of the Jheh1 gene,
which codes for an enzyme degrading juvenile hormone - PMC
Journal
Vavilovskii zhurnal genetiki i selektsii
CDKL1 potentiates the antitumor efficacy of radioimmunotherapy by binding to transcription factor YBX1 and blocking PD-L1 expression in lung cancer
Journal
Journal of experimental & clinical cancer research : CR
Species
Homo sapiens,Mus musculus
The NTE domain of PTEN/ promotes cancer progression by interacting with WDR5 via its SSSRRSS motif - PMC
Journal
Cell death & disease
ANXA9 facilitates S100A4 and promotes breast cancer progression through modulating STAT3 pathway - PMC
Journal
Cell death & disease
Tet2 acts in the lateral habenula to regulate social preference in mice
PRMT6 methylation of STAT3 regulates tumor metastasis in breast cancer - PMC
Journal
Cell death & disease
Histone H3Y99sulf regulates hepatocellular carcinoma responding to hypoxia
Journal
The Journal of biological chemistry
MiR-122-5p regulates the mevalonate pathway by targeting p53 in non-small cell lung cancer - PMC
Journal
Cell death & disease
Distribution and characterization of extrachromosomal circular DNA in colorectal cancer - PMC
Journal
Molecular biomedicine
Molecular cloning, expression and functional analysis of STAT2 in orange-spotted grouper, Epinephelus coioides