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Human PD-1/CD279 Sandwich Immunoassay
Recommended Concentration | Sample | ||
---|---|---|---|
ELISA | Capture | 0.5-2ug/mL | Rabbit anti-Human PD-1/CD279 mAb(Cat. No.RMK0127) |
Detection | 0.025-0.1ng/mL | Rabbit anti-Human PD-1/CD279 mAb(Cat. No.RMK0128) | |
Standard | 15.63-1000pg/mL | Recombinant Human PD-1/CD279 Protein(Cat. No.RP00067) | |
Multiplex | Capture | 3-20ug/mL | Rabbit anti-Human PD-1/CD279 mAb(Cat. No.RMK0398) |
Detection | 0.017-2ug/mL | Rabbit anti-Human PD-1/CD279 mAb(Cat. No.RMK0128) | |
Standard | 6.86-5000pg/mL | Recombinant Human PD-1/CD279 Protein(Cat. No.RP00067) |
Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity.