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Human IL-1 alpha Sandwich Immunoassay
Recommended Concentration | Sample | ||
---|---|---|---|
ELISA | Capture | 1-4ug/mL | Rabbit anti-Human IL-1 alpha mAb(Cat. No.RMK0148) |
Detection | 0.005-0.02ug/mL | Rabbit anti-Human IL-1 alpha mAb(Cat. No.RMK0149) | |
Standard | 7.8-500pg/mL | Recombinant Human IL-1 alpha Protein(Cat. No.RP00098) |
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.